Results 41 to 50 of about 9,434,436 (330)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
On December 18, 2023, an Ms 6.2 earthquake jolted Jishishan County in the Linxia Hui Autonomous Prefecture in Northwest China’s Gansu Province, causing substantial casualties and building collapses.
TaiRan Xu +7 more
doaj +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Design and characteristic analysis of hybrid OFD–LFM–PC waveforms in the MIMO radar
In this study, a new set of hybrid orthogonal frequency division–linear frequency modulation–phase coded (OFD–LFM–PC) waveforms are proposed to improve the detection performance of multiple-input-multiple-output (MIMO) radars.
Sheng Hong +4 more
doaj +1 more source
Focal mechanism determination of Nima MS6.6 and MS4.8 earthquakes in Tibet in 2020
A MS6.6 earthquake occurred at 4:07 am on July 23,2020 in Nima County,Nagqu,Tibet Autonomous Region. The location of the main shock is 33.19°N,86.81°E,and the focal depth is 10 km.
Xumao Li +3 more
doaj +1 more source
Greenways and Ecological Networks: Concepts, Differences, Similarities [PDF]
In recent decades green infrastructure (GI) frameworks have been widely used for developing theoretical and practical models of sustainable land reorganization.
Balestrieri, Mara, Ganciu, Amedeo
core +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
In this paper, the regional full waveform inversion of the broadband waveforms from China Seismic Network were conducted, and the focal mechanism solutions of the 24 earthquakes with MS≥4.0 in the mainland of China from April 1 to June 30, 2022 were ...
Shanshan Liang +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source

