Results 31 to 40 of about 162,651 (310)

δ-Protocadherins regulate neural progenitor cell division by antagonizing Ryk and Wnt/β-catenin signaling

iScience, 2021
Summary: The division of neural progenitor cells provides the cellular substrate from which the nervous system is sculpted during development. The δ-protocadherin family of homophilic cell adhesion molecules is essential for the development of the ...
Sayantanee Biswas, Michelle R. Emond, Kurtis P. Chenoweth, James D. Jontes   +3 more
doaj   +1 more source

Molecular cloning and characterization of B-cadherin, a novel chick cadherin. [PDF]

, 1991
Calcium-dependent cell-cell adhesion is mediated in large part by a set of homologous integral membrane glycoproteins termed cadherins. In this report, antibodies to conserved domains in previously described cadherins have been used to isolate cDNAs ...
Napolitano, EW, Reichardt, LF, Venstrom, K, Wheeler, EF   +3 more
core   +2 more sources

The characteristics of hematopoietic stem cells from autoimmune-prone mice and the role of neural cell adhesion molecules in abnormal proliferation of these cells in MRL/lpr mice

Haematologica, 2007
Background and Objectives Using various animal models for autoimmune diseases, we have previously shown that such diseases are stem cell disorders.1 In order to understand how autoimmune diseases develop, we investigated the distinct qualitative ...
Xiaoli Wang, Hiroko Hisha, Wenhao Cui, Changye Song, Tomomi Mizokami, Satoshi Okazaki, Qing Li, Wei Feng, Junko Kato, Shiwen Jiang, Hongxue Fan, Susumu Ikehara   +11 more
doaj   +1 more source

Molecular Mechanisms of L1 and NCAM Adhesion Molecules in Synaptic Pruning, Plasticity, and Stabilization

Frontiers in Cell and Developmental Biology, 2021
Mammalian brain circuits are wired by dynamic formation and remodeling during development to produce a balance of excitatory and inhibitory synapses. Synaptic regulation is mediated by a complex network of proteins including immunoglobulin (Ig)- class ...
Bryce W. Duncan, Kelsey E. Murphy, Patricia F. Maness   +2 more
doaj   +1 more source

Neural Stem Cell Spreading on Lipid Based Artificial Cell Surfaces, Characterized by Combined X-ray and Neutron Reflectometry [PDF]

, 2010
We developed a bioadhesive coating based on a synthetic peptide-conjugate (AK-cycloRGDfC]) which contains multiples of the arginyl-glycyl-aspartic acid (RGD) amino acid sequence.
Bert Nickel, Emilia Madarasz, Gabor Mezo, Marko, Martin Huth, Mezo, Pfaff, Samira Hertrich, Szokan, Wang   +9 more
core   +3 more sources

CHL1 and NrCAM are primarily expressed in low grade pediatric neuroblastoma

Open Medicine, 2019
Neural cell adhesion molecules like close homolog of L1 protein (CHL1) and neuronal glia related cell adhesion molecule (NrCAM) play an important role in development and regeneration of the central nervous system.
Wachowiak Robin, Mayer Steffi, Suttkus Anne, Martynov Illya, Lacher Martin, Melling Nathaniel, Izbicki Jakob R., Tachezy Michael   +7 more
doaj   +1 more source

Expression of E-cadherin, Slug and NCAM and its relationship to tumor invasiveness in patients with acromegaly

Brazilian Journal of Medical and Biological Research, 2017
Pituitary adenomas account for 10–15% of primary intracranial tumors. Growth hormone (GH)-secreting adenomas account for 13% of all pituitary adenomas and cause acromegaly.
G.A. Mendes, T. Haag, G. Trott, C.G.S.L. Rech, N.P. Ferreira, M.C. Oliveira, M.B. Kohek, J.F.S. Pereira-Lima   +7 more
doaj   +1 more source

Low expression of neural cell adhesion molecule, CD56, is associated with low efficacy of bortezomib plus dexamethasone therapy in multiple myeloma. [PDF]

PLoS ONE, 2018
Bortezomib (Btz) is an active agent used to treat multiple myeloma (MM). Not all patients who receive Btz-containing therapy show a favorable response.
Takashi Yoshida, Masaki Ri, Shiori Kinoshita, Tomoko Narita, Haruhito Totani, Reham Ashour, Asahi Ito, Shigeru Kusumoto, Takashi Ishida, Hirokazu Komatsu, Shinsuke Iida   +10 more
doaj   +1 more source

Melanophore migration and survival during zebrafish adult pigment stripe development require the immunoglobulin superfamily adhesion molecule Igsf11. [PDF]

, 2012
The zebrafish adult pigment pattern has emerged as a useful model for understanding the development and evolution of adult form as well as pattern-forming mechanisms more generally.
Eom, Dae Seok, Gordon, Tiffany N, Inoue, Shinya, Kondo, Shigeru, Parichy, David M, Patterson, Larissa B, Slingwine, Rebecca, Watanabe, Masakatsu   +7 more
core   +2 more sources

Adhesion of retinal cells to gold surfaces by biomimetic molecules

Frontiers in Cell and Developmental Biology
BackgroundNeural cell-electrode coupling is crucial for effective neural and retinal prostheses. Enhancing this coupling can be achieved through surface modification and geometrical design to increase neuron-electrode proximity.
Gal Shpun, Gal Shpun, Gal Shpun, Amos Markus, Amos Markus, Nairouz Farah, Nairouz Farah, Zeev Zalevsky, Zeev Zalevsky, Yossi Mandel, Yossi Mandel, Yossi Mandel   +11 more
doaj   +1 more source