Results 91 to 100 of about 483,558 (265)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Neural geometry from mixed sensorimotor selectivity for predictive sensorimotor control
eLifeAlthough recent studies suggest that activity in the motor cortex, in addition to generating motor outputs, receives substantial information regarding sensory inputs, it is still unclear how sensory context adjusts the motor commands.
Yiheng Zhang +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Probabilistic Encoding Models for Multivariate Neural Data
Frontiers in Neural Circuits, 2019 A key problem in systems neuroscience is to characterize how populations of neurons encode information in their patterns of activity. An understanding of the encoding process is essential both for gaining insight into the origins of perception and for ...
Marcus A. Triplett, Geoffrey J. Goodhill
doaj +1 more source
Spatial Coding Techniques for Molecular MIMO
, 2017 This paper studies spatial diversity techniques applied to multiple-input multiple-output (MIMO) diffusion-based molecular communications (DBMC). Two types of spatial coding techniques, namely Alamouti-type coding and repetition MIMO coding are suggested
Chae, Chan-Byoung +3 more
core +1 more source
Neural Codes for Image Retrieval [PDF]
, 2014 to appear at ECCV ...
Artem Babenko +3 more
openaire +2 more sources
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Metaheuristic Optimisation Algorithms for Tuning a Bioinspired Retinal Model
Sensors, 2019 A significant challenge in neuroscience is understanding how visual information is encoded in the retina. Such knowledge is extremely important for the purpose of designing bioinspired sensors and artificial retinal systems that will, in so far as may be
Rubén Crespo-Cano +3 more
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
The effect of neural adaptation of population coding accuracy
, 2011 Most neurons in the primary visual cortex initially respond vigorously when a preferred stimulus is presented, but adapt as stimulation continues. The functional consequences of adaptation are unclear.
Cortes, J. M. +5 more
core +2 more sources