Results 71 to 80 of about 483,558 (265)

Parallel processing of past and future memories through reactivation and synaptic plasticity mechanisms during sleep

Nature Communications
Every day, we experience new episodes and store new memories. Although memories are stored in corresponding engram cells, how different sets of engram cells are selected for current and next episodes, and how they create their memories, remains unclear ...
Khaled Ghandour, Tatsuya Haga, Noriaki Ohkawa, Chi Chung Alan Fung, Masanori Nomoto, Mostafa R. Fayed, Hirotaka Asai, Masaaki Sato, Tomoki Fukai, Kaoru Inokuchi   +9 more
doaj   +1 more source

Deep Networks for Image Super-Resolution with Sparse Prior

, 2015
Deep learning techniques have been successfully applied in many areas of computer vision, including low-level image restoration problems. For image super-resolution, several models based on deep neural networks have been recently proposed and attained ...
Han, Wei, Huang, Thomas, Liu, Ding, Wang, Zhaowen, Yang, Jianchao   +4 more
core   +1 more source

Neural Coding: The enigma of the brain [PDF]

Current Biology, 1995
AbstractInformation may be coded in neuronal firing patterns in other ways than the instantaneous action-potential frequency; but proving that the brain uses a particular alternative code will not be easy.
Stevens, Charles F., Zador, Anthony
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Cortical response states for enhanced sensory discrimination

eLife, 2017
Brain activity during wakefulness is characterized by rapid fluctuations in neuronal responses. Whether these fluctuations play any role in modulating the accuracy of behavioral responses is poorly understood.
Diego A Gutnisky, Charles Beaman, Sergio E Lew, Valentin Dragoi   +3 more
doaj   +1 more source

Intensity Coding in Two-Dimensional Excitable Neural Networks

, 2004
In the light of recent experimental findings that gap junctions are essential for low level intensity detection in the sensory periphery, the Greenberg-Hastings cellular automaton is employed to model the response of a two-dimensional sensory network to ...
Bair, Bardou, Bokil, Chialvo, Cleland, Copelli, Deans, Firestein, Greenberg, Hidaka, Kaplan, Kosaka, Lewis, Mauro Copelli, Osame Kinouchi, Purves, Rospars, Simões-de-Souza, Stevens, Tomé, Traub, Wiener, Zhang, Zorzenon dos Santos   +23 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Decoding neural responses to temporal cues for sound localization

eLife, 2013
The activity of sensory neural populations carries information about the environment. This may be extracted from neural activity using different strategies.
Dan FM Goodman, Victor Benichoux, Romain Brette   +2 more
doaj   +1 more source

Deciphering a neural code for vision [PDF]

Proceedings of the National Academy of Sciences, 1997
Deciphering the information that eyes, ears, and other sensory organs transmit to the brain is important for understanding the neural basis of behavior. Recordings from single sensory nerve cells have yielded useful insights, but single neurons generally do not mediate behavior; networks of neurons do.
C, Passaglia, F, Dodge, E, Herzog, S, Jackson, R, Barlow   +4 more
openaire   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source