Results 101 to 110 of about 134,028 (308)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Roles of cardiac neural crest cells in cardiovascular development and associated congenital defects-an integrated review

open access: yesTranslational Research in Anatomy
The development of the cardiovascular system is a highly intricate process that encompasses various types of cells and communication pathways. During embryonic development, specific cells differentiate and organize to form complex structures of the heart
Worku Abie Liyew   +6 more
doaj   +1 more source

Fast Synchronization of Perpetual Grouping in Laminar Visual Cortical Circuits [PDF]

open access: yes, 2004
Perceptual grouping is well-known to be a fundamental process during visual perception, notably grouping across scenic regions that do not receive contrastive visual inputs. Illusory contours are a classical example of such groupings.
Grossberg, Stephen, Yazdanbakhsh, Arash
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

A New and Noninvasive Antidromic Technique for Electrophysiological Evaluation of the Feet Digital Nerves

open access: yesمجله دانشکده پزشکی اصفهان, 2019
Background: The purpose of this study was to introduce a new and noninvasive technique for antidromic electrophysiological evaluation of the feet digital nerves to find normal values of amplitudes and nerve conduction velocity (NCV).
Seyed Pezhman Madani   +4 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Electrophysiologic studies in leprosy

open access: yesArquivos de Neuro-Psiquiatria, 1992
The author reviews the literature on electromyography and nerve conduction velocity studies in leprosy. It is concluded that these studies can be helpful in the early diagnosis of neural involvement, in the elucidation of pathophysiological mechanisms ...
Joaquim P. Brasil-Neto
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Auditory brainstem response anomalies despite normal hearing in a child with Down syndrome: case-based insight

open access: yesThe Egyptian Journal of Otolaryngology
Background Down syndrome (DS) is associated with a spectrum of cognitive and sensory impairments, including a high prevalence of hearing difficulties.
Praveen Prakash   +3 more
doaj   +1 more source

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