Results 51 to 60 of about 124,789 (305)

Crossed Aphasia in a Patient with Anaplastic Astrocytoma of the Non-Dominant Hemisphere [PDF]

open access: yes, 2017
Aphasia describes a spectrum of speech impairments due to damage in the language centers of the brain. Insult to the inferior frontal gyrus of the dominant cerebral hemisphere results in Broca\u27s aphasia - the inability to produce fluent speech.
Anand, Neil   +3 more
core   +2 more sources

Graph Dynamical Networks for Unsupervised Learning of Atomic Scale Dynamics in Materials

open access: yes, 2019
Understanding the dynamical processes that govern the performance of functional materials is essential for the design of next generation materials to tackle global energy and environmental challenges.
France-Lanord, Arthur   +4 more
core   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Discussion of the technology and research in fuel injectors common rail system [PDF]

open access: yes, 2017
Common rail is one of the most important components in a diesel and gasoline direct injection system. It features a high-pressure (100 bar) fuel rail feeding solenoid valves, as opposed to a low-pressure fuel pump feeding unit injectors. Third-generation
Ishak, Izuan Amin   +5 more
core  

Repeating Spatial-Temporal Motifs of CA3 Activity Dependent on Engineered Inputs from Dentate Gyrus Neurons in Live Hippocampal Networks. [PDF]

open access: yes, 2016
Anatomical and behavioral studies, and in vivo and slice electrophysiology of the hippocampus suggest specific functions of the dentate gyrus (DG) and the CA3 subregions, but the underlying activity dynamics and repeatability of information processing ...
Bhattacharya, Aparajita   +4 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Electrochemical polymerization of conducting polymers in living neural tissue [PDF]

open access: yesJournal of Neural Engineering, 2007
A number of biomedical devices require extended electrical communication with surrounding tissue. Significant improvements in device performance would be achieved if it were possible to maintain communication with target cells despite the reactive, insulating scar tissue that forms at the device-tissue interface.
David C. Martin   +2 more
openaire   +3 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Simulation of fiber conduction block using high frequency alternative current with asymmetric biphasic waveform and its mechanism of action

open access: yesمجله پژوهش در علوم توانبخشی, 2014
Introduction: High Frequency Alternating Currents is a safe, reversible and selective method for nerve conduction block that has been under study during the last decade as a treatment for the diseases involving abnormal neural impulses. However, reducing
Alireza Arianfar, Amin Mahnam
doaj   +1 more source

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