Results 31 to 40 of about 120,010 (245)

Continuous adaptive nonlinear model predictive control using spiking neural networks and real-time learning

Neuromorphic Computing and Engineering
Model predictive control (MPC) is a prominent control paradigm providing accurate state prediction and subsequent control actions for intricate dynamical systems with applications ranging from autonomous driving to star tracking.
Raz Halaly, Elishai Ezra Tsur
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Hierarchical Deep Learning Neural Network (HiDeNN): An artificial intelligence (AI) framework for computational science and engineering

Computer Methods in Applied Mechanics and Engineering, 2021
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Saha, Sourav, Gan, Zhengtao, Cheng, Lin, Gao, Jiaying, Kafka, Orion L., Xie, Xiaoyu, Li, Hengyang, Tajdari, Mahsa, Kim, H. Alicia, Liu, Wing Kam   +9 more
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The role of inhibition in modeling decision making with spiking neural networks

Frontiers in Neuroinformatics
Decision making (DM) requires coordination of elementary information processes subserved by a distributed network of brain areas. Computational models help to understand these processes, but most of the existing models focus on simulating only one of the
Bartłomiej Król-Józaga, Peter Duggins, Anna Broniec-Wójcik, Szymon Wichary   +3 more
doaj   +1 more source

Perform Like an Engine: A Closed-Loop Neural-Symbolic Learning Framework for Knowledge Graph Inference

, 2021
The full version of a long paper accepted to COLING 2022, 9 pages, 6 figures, 3 ...
Guanglin Niu, Bo Li 0006, Yongfei Zhang, Shiliang Pu   +3 more
openaire   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cost Index Predictions for Construction Engineering Based on LSTM Neural Networks

Advances in Civil Engineering, 2020
In recent years, the cost index predictions of construction engineering projects are becoming important research topics in the field of construction management. Previous methods have limitations in reasonably reflecting the timeliness of engineering cost
Jiacheng Dong, Yuan Chen, Gang Guan
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source