Results 251 to 260 of about 614,321 (322)

A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds

Advanced Healthcare Materials, EarlyView.
Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico, Irene Chiesa, Angela Toffano, Alessio Esposito, Piera Mancini, Chiara Magliaro, Angeliki Louvi, Carmelo De Maria, Marco Onorati   +8 more
wiley   +1 more source

Altered GABAergic signaling and chloride homeostasis in eye movement circuits during late neurodevelopment: implications for Alzheimer's disease therapy. [PDF]

Front Pharmacol
Porcher C, Rivera C, Medina I, Koric L.
europepmc   +1 more source

TDP-43 regulates LC3ylation in neural tissue through ATG4B cryptic splicing inhibition [PDF]

Pascual Torres, Santiago Rico-Rios, Miriam Ceron-Codorniu, Marta Santacreu-Vilaseca, David Seoane-Miraz, Yahya E. Jad, Victòria Ayala, Guillermo Mariño, María Beltran, Maria P. Miralles, Pol Andrés‐Benito, Joaquín Fernández‐Irigoyen, Enrique Santamaría, Carlos López-Otı́n, Rosa M. Soler, Mónica Povedano, Isidró Ferrer, Reinald Pamplona, Matthew J. A. Wood, Miguel A. Varela, Manuel Portero-Otı́n   +20 more
openalex   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

A central CeA-LC-PVH circuit mediates stress-induced osteopenia via skeletal sympathetic nerves in male mice. [PDF]

Sci Adv
Zhao WJ, Lu YX, Fan GD, Zhou J, Tan CY, Huang PP, Ye B, Xie F, Zhu Y, Wang BH, Liu CH, Dou XY, Dong YL, Hu XY.   +13 more
europepmc   +1 more source

Inhibition of neural activities by photothermal effects of polydopamine film with patterned illumination

, 2019
Hyunsoo Jang, Yoonkey Nam
openalex   +1 more source

Controlling Intestinal Organoid Polarity using Synthetic Dynamic Hydrogels Decorated with Laminin‐Derived IKVAV Peptides

Advanced Healthcare Materials, EarlyView.
Design rules are presented to control intestinal organoid polarity in fully synthetic hydrogels. The laminin‐derived IKVAV sequence is crucial to obtain correct intestinal organoid polarity. Increasing hydrogel dynamics further supports the growth of correctly polarized intestinal organoids, while a bulk level of stiffness (G’ ≈ 0.7 kPa) is crucial to ...
Laura Rijns, Joost A. P. M. Wijnakker, Victor A. Veenbrink, Riccardo Bellan, Fenna W. B. Craenmehr, Simone I. S. Hendrikse, Johnick F. van Sprang, Wim de Lau, E. W. Meijer, Hans Clevers, Patricia Y. W. Dankers   +10 more
wiley   +1 more source

Neural representation of proactive and reactive inhibitory control adaptations across sensory modalities. [PDF]

Cereb Cortex
Nakajima F, Ikarashi K, Yamashiro K, Ochi G, Fujimoto T, Sato D.   +5 more
europepmc   +1 more source

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

Advanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel, Sailee Sham Lavekar, Ronak Jaisalmeria, Suki Oji, Jazmine Jayasi, Caroline Cvetkovic, Robert Krencik   +6 more
wiley   +1 more source

Neuronal heterogeneity of normalization strength in a circuit model. [PDF]

Sci Adv
Song D, Ruff D, Cohen M, Huang C.
europepmc   +1 more source