Results 101 to 110 of about 3,692,894 (287)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Cost weighting for neural machine translation domain adaptation

, 2017
In this paper, we propose a new domain adaptation technique for neural machine translation called cost weighting, which is appropriate for adaptation scenarios in which a small in-domain data set and a large general-domain data set are available.
Cherry, Colin, Foster, George, Larkin, Samuel, Chen, Boxing   +3 more
core   +2 more sources

Automatic sign language translation: a review of neural network methods for recognition and synthesis of spoken and signed language

Научно-технический вестник информационных технологий, механики и оптики
A review of modern methods and technologies for automatic machine translation for the deaf and hard of hearing is presented, including recognition and synthesis of both spoken and sign languages.
D. V. Ivanko, D. A. Ryumin
doaj   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Debugging Neural Machine Translations

CoRR, 2018
In this paper, we describe a tool for debugging the output and attention weights of neural machine translation (NMT) systems and for improved estimations of confidence about the output based on the attention. The purpose of the tool is to help researchers and developers find weak and faulty example translations that their NMT systems produce without ...
openaire   +3 more sources

Neural Machine Translation from Simplified Translations

CoRR, 2016
Submitted to EACL 2017 Short ...
Josep Maria Crego, Jean Senellart
openaire   +3 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Leveraging rule-based machine translation knowledge for under-resourced neural machine translation models

, 2019
Rule-based machine translation is a machine translation paradigm where linguistic knowledge is encoded by an expert in the form of rules that translate from source to target language. While this approach grants total control over the output of the system,
Masoud, Maraim, Chakravarthi, Bharathi Raja, Casas, Noe, Arcan, Mihael, Chakravarth, Bharathi Raja, Torregrosa, Daniel, Pasricha, Nivranshu, Alonso, Juan   +7 more
core   +1 more source