Results 91 to 100 of about 47,700 (259)

Synchronous Bidirectional Neural Machine Translation

Transactions of the Association for Computational Linguistics, 2019
Existing approaches to neural machine translation (NMT) generate the target language sequence token-by-token from left to right. However, this kind of unidirectional decoding framework cannot make full use of the target-side future contexts which can be ...
Zhou, Long, Zhang, Jiajun, Zong, Chengqing   +2 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Memory-augmented Neural Machine Translation [PDF]

Proceedings of the 2017 Conference on Empirical Methods in Natural Language Processing, 2017
Neural machine translation (NMT) has achieved notable success in recent times, however it is also widely recognized that this approach has limitations with handling infrequent words and word pairs. This paper presents a novel memory-augmented NMT (M-NMT) architecture, which stores knowledge about how words (usually infrequently encountered ones) should
Feng, Yang, Zhang, Shiyue, Zhang, Andi, Wang, Dong, Abel, Andrew   +4 more
openaire   +4 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Machine Translation Indonesian Bengkulu Malay Using Neural Machine Translation-LSTM

IJCCS (Indonesian Journal of Computing and Cybernetics Systems)
The machine translator is an application in Natural Language Processing (NLP) that focuses on translating between languages. Several previous research have used Statistical Machine Translation (SMT) with a parallel corpus of Indonesian and Bengkulu Malay
Bella Okta Sari Miranda, Herman Yuliansyah, Muhammad Kunta Biddinika   +2 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Automatic sign language translation: a review of neural network methods for recognition and synthesis of spoken and signed language

Научно-технический вестник информационных технологий, механики и оптики
A review of modern methods and technologies for automatic machine translation for the deaf and hard of hearing is presented, including recognition and synthesis of both spoken and sign languages.
D. V. Ivanko, D. A. Ryumin
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source