Results 71 to 80 of about 240,752 (266)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Improving Transformer-Based Neural Machine Translation with Prior Alignments

open access: yesComplexity, 2021
Transformer is a neural machine translation model which revolutionizes machine translation. Compared with traditional statistical machine translation models and other neural machine translation models, the recently proposed transformer model radically ...
Thien Nguyen   +3 more
doaj   +1 more source

A review of existing Machine Translation Approaches, their Challenges and Evaluation Metrics

open access: yesPakistan Journal of Engineering Technology & Science, 2023
Machine translation is the process of translating a natural language into another. The primary goal of machine translation is to bridge the linguistic gap between languages.
Naseer Ahmed
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

Neural machine translation system for the Kazakh language based on synthetic corpora

open access: yesMATEC Web of Conferences, 2019
The lack of big parallel data is present for the Kazakh language. This problem seriously impairs the quality of machine translation from and into Kazakh.
Tukeyev Ualsher   +2 more
doaj   +1 more source

Custom neural machine translation

open access: yes, 2022
This chapter gives an overview of the theoretical and practical implications of customizing machine translation (MT) to make it fit for a particular purpose. The chapter is written for readers who have just a basic knowledge of MT, but experts who are seeking new ways of explaining MT to non-experts may also find it useful.
openaire   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical applications, challenges, and future directions

open access: yesArthritis Care &Research, Accepted Article.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Synchronous Bidirectional Neural Machine Translation

open access: yesTransactions of the Association for Computational Linguistics, 2019
Existing approaches to neural machine translation (NMT) generate the target language sequence token-by-token from left to right. However, this kind of unidirectional decoding framework cannot make full use of the target-side future contexts which can be ...
Zhou, Long   +2 more
doaj   +1 more source

Unsupervised Neural Machine Translation

open access: yes, 2017
In spite of the recent success of neural machine translation (NMT) in standard benchmarks, the lack of large parallel corpora poses a major practical problem for many language pairs. There have been several proposals to alleviate this issue with, for instance, triangulation and semi-supervised learning techniques, but they still require a strong cross ...
Artetxe Zurutuza, Mikel   +3 more
openaire   +3 more sources

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