Results 41 to 50 of about 644,633 (264)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Scaling Up Bayesian Neural Networks with Neural Networks
Trans. Mach. Learn. Res., 2023 25 ...
Zahra Moslemi +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Abundant exact solutions of higher-order dispersion variable coefficient KdV equation
Open Physics, 2022 In this article, various exact solutions of the fifth-order variable coefficient KdV equation with higher-order dispersion term are studied. Because of the complexity of the exact solution of the variable coefficient t, it has a certain influence on the ...
Zhao Zhen, Pang Jing
doaj +1 more source
Diagnostyka, 2021 Installations and the detection of their faults has become a major challenge. In order to develop a reliable approach for monitoring and diagnosis faults of these components, a test rig was mounted.
Khoualdia Tarek +4 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Dithering suppresses half-harmonic neural synchronisation to photic stimulation in humans
Brain StimulationBackground:: While entraining neural rhythms using brain stimulation has been suggested as a therapeutic mechanism to normalise brain activity in conditions such as depression, chronic pain, or Alzheimer’s disease, periodic stimulation can also ...
Benoit Duchet +9 more
doaj +1 more source
Significant subgraph mining for neural network inference with multiple comparisons correction
Network Neuroscience, 2023 We describe how the recently introduced method of significant subgraph mining can be employed as a useful tool in neural network comparison. It is applicable whenever the goal is to compare two sets of unweighted graphs and to determine differences in ...
Aaron J. Gutknecht, Michael Wibral
doaj +1 more source