Results 51 to 60 of about 2,150,519 (283)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Abundant exact solutions of higher-order dispersion variable coefficient KdV equation
Open Physics, 2022 In this article, various exact solutions of the fifth-order variable coefficient KdV equation with higher-order dispersion term are studied. Because of the complexity of the exact solution of the variable coefficient t, it has a certain influence on the ...
Zhao Zhen, Pang Jing
doaj +1 more source
Analysis of Neural Networks in Terms of Domain Functions [PDF]
, 2002 Despite their success-story, artificial neural networks have one major disadvantage compared to other techniques: the inability to explain comprehensively how a trained neural network reaches its output; neural networks are not only (incorrectly) seen as
Slump, Cees +2 more
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diagnostyka, 2021 Installations and the detection of their faults has become a major challenge. In order to develop a reliable approach for monitoring and diagnosis faults of these components, a test rig was mounted.
Khoualdia Tarek +4 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Significant subgraph mining for neural network inference with multiple comparisons correction
Network Neuroscience, 2023 We describe how the recently introduced method of significant subgraph mining can be employed as a useful tool in neural network comparison. It is applicable whenever the goal is to compare two sets of unweighted graphs and to determine differences in ...
Aaron J. Gutknecht, Michael Wibral
doaj +1 more source
Learning text representation using recurrent convolutional neural network with highway layers [PDF]
, 2016 Recently, the rapid development of word embedding and neural networks has brought new inspiration to various NLP and IR tasks. In this paper, we describe a staged hybrid model combining Recurrent Convolutional Neural Networks (RCNN) with highway layers ...
Luo, Rui +3 more
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source