Results 211 to 220 of about 6,298,151 (304)

Nasal Tuft Cell Markers Are Predictive of Overall Survival in Sinonasal Neuroendocrine and Sinonasal Undifferentiated Carcinomas

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinonasal neuroendocrine carcinoma (SNEC) and sinonasal undifferentiated carcinoma (SNUC) are rare aggressive malignancies with no established prognostic markers. Because features of POU2F3+ small cell lung carcinomas have been identified in both tumors, we evaluated immunostaining for POU2F3, a tuft cell transcription factor, and ...
Nikolina Dioufa, Ricardo V. Bruneto, Jennifer E. Douglas, Nithin D. Adappa, James N. Palmer, Noam A. Cohen, Michael A. Kohanski   +6 more
wiley   +1 more source

Comparative Gene Co-expression Network Analysis of Proviral and Antiviral Responses to Dengue Virus-2 (DENV-2) and Zika Virus (ZIKV) Infection in Human Neural Progenitor Cells (hNPCs). [PDF]

PLoS One
Owaresat JK, Dey D, Siam MAH, Anam MA, Siddiki AZ.   +4 more
europepmc   +1 more source

T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy

Annals of Neurology, EarlyView.
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes, Lukas Henning, Karen M. J. van Loo, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch   +6 more
wiley   +1 more source

3D bioprinted human iPSC-derived neural progenitor cells as a novel platform for studying neurogenic niche. [PDF]

APL Bioeng
Machado LS, Ferreira PS, Pires MR, Bim LV, de Oliveira NH, Salles GR, Ferreira ND, Cruz EM, Porcionatto MA.   +8 more
europepmc   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

Patient-Derived Cortical Organoids Reveal Senescence of Neural Progenitor Cells in Hutchinson-Gilford Progeria Syndrome. [PDF]

Aging Cell
Jeon S, Park CS, Hong J, Kim J, Lee YJ, Hur JK, Lee JY.   +6 more
europepmc   +1 more source

Distribution of doublecortin in the developing retina of birds: A comparative analysis

The Anatomical Record, EarlyView.
Abstract The avian retina presents an elegant and highly accessible model for investigating the spatial and temporal dynamics of neurogenesis within the central nervous system. In recent years, the microtubule cytoskeleton has emerged not merely as a structural scaffold, but as a dynamic regulator of the transition of a morphologically homogeneous pool
Javier Francisco‐Morcillo, José Antonio de Mera‐Rodríguez, Violeta Calle‐Guisado, Gervasio Martín‐Partido, Joaquín Rodríguez‐León, Guadalupe Álvarez‐Hernán   +5 more
wiley   +1 more source

A map of enhancer regions in primary human neural progenitor cells using capture STARR-seq. [PDF]

Genome Res
Gaynor-Gillett SC, Cheng L, Shi M, Liu J, Wang G, Spector M, Guo Q, Qi L, Flaherty M, Wall M, Hwang A, Gu M, Chen Z, Chen Y, PsychENCODE Consortium, Moran JR, Zhang J, Lee D, Gerstein M, Geschwind D, White KP.   +20 more
europepmc   +1 more source

Cross‐Species Single‐Cell Comparative Analysis Reveals Gluconeogenic Features of Hepatocytes in Ruminants

Animal Research and One Health, EarlyView.
In this study, we used cross‐species comparisons to identify ruminant hepatocyte features. We also identified potential genes and TFs involved in coordinating gluconeogenesis in ruminant hepatocytes. By integrating single‐cell data with population genetic analyses, we further identified candidate genetic variation in glucose metabolism and ...
Yaqi Zhou, Wuqiang Huo, Yingran Liu, Yihang Liu, Fei Wang, Tao Shi, Yu Jiang   +6 more
wiley   +1 more source

DNA damage-induced senescence reshapes transcriptomic and functional landscape of human neural progenitor cells

Jose NV, Assir MZK, Soper O, Janssens S, Platt B, Kang E.   +5 more
europepmc   +1 more source