Results 121 to 130 of about 2,440,466 (317)
Subthalamic hGAD65 Gene Therapy and Striatum TH Gene Transfer in a Parkinson’s Disease Rat Model
Neural Plasticity, 2013 The aim of the present study is to detect a combination method to utilize gene therapy for the treatment of Parkinson’s disease (PD). Here, a PD rat model is used for the in vivo gene therapy of a recombinant adeno-associated virus (AAV2) containing a ...
Deyu Zheng +5 more
doaj +1 more source
Aging, computation, and the evolution of neural regeneration processes [PDF]
arXiv, 2019 Metazoans are capable of gathering information from their environments and respond in predictable ways. These computational tasks are achieved by means of more or less complex networks of neurons. Task performance must be reliable over an individual's lifetime and must deal robustly with the finite lifespan of cells or with connection failure ...
arxiv
Optimization of Operation Strategy for Primary Torque based hydrostatic Drivetrain using Artificial Intelligence [PDF]
arXiv, 2020 A new primary torque control concept for hydrostatics mobile machines was introduced in 2018. The mentioned concept controls the pressure in a closed circuit by changing the angle of the hydraulic pump to achieve the desired pressure based on a feedback system. Thanks to this concept, a series of advantages are expected.
arxiv
Direct Ink Writing of Conductive Hydrogels
Advanced Functional Materials, EarlyView.This review examines the use of direct ink writing (DIW) for fabricating conductive hydrogels with customizable 3D structures. It outlines the rheological requirements for successful DIW, followed by an exploration of the materials and ink formulations used to impart electronic and/or ionic conductivity to hydrogels while maintaining printability ...
Monica Ho +6 more
wiley +1 more source
Continuum percolation theory of epimorphic regeneration [PDF]
arXiv, 2017 A biophysical model of epimorphic regeneration based on a continuum percolation process of fully penetrable disks in two dimensions is proposed. All cells within a randomly chosen disk of the regenerating organism are assumed to receive a signal in the form of a circular wave as a result of the action/reconfiguration of neoblasts and neoblast-derived ...
arxiv
Adipose Stem Cell-Based Clinical Strategy for Neural Regeneration: A Review of Current Opinion
Stem Cells International, 2019 Nerve injury is a critical problem in the clinic. Nerve injury causes serious clinic issues including pain and dysfunctions for patients. The disconnection between damaged neural fibers and muscles will result in muscle atrophy in a few weeks if no ...
Yu-hao Wang +4 more
semanticscholar +1 more source
Regeneration Through in vivo Cell Fate Reprogramming for Neural Repair
Frontiers in Cellular Neuroscience, 2020 The adult mammalian central nervous system (CNS) has very limited regenerative capacity upon neural injuries or under degenerative conditions. In recent years, however, significant progress has been made on in vivo cell fate reprogramming for neural ...
Wenjiao Tai, Xiao-Ming Xu, Chun-li Zhang
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.This study introduces a conductive nerve guidance conduit integrated with wireless electrical stimulation through alternating magnetic fields, which induces currents and creates a supportive microenvironment for nerve regeneration. In vivo studies show that this approach significantly enhanced myelin restoration, gastrocnemius muscle regeneration ...
Shiheng Liu +7 more
wiley +1 more source
Ascorbic Acid Facilitates Neural Regeneration After Sciatic Nerve Crush Injury
Frontiers in Cellular Neuroscience, 2019 Ascorbic acid (AA) is an essential micronutrient that has been safely used in the clinic for many years. The present study indicates that AA has an unexpected function in facilitating nerve regeneration. Using a mouse model of sciatic nerve crush injury,
Lixia Li +12 more
semanticscholar +1 more source
Bioresorbable and Wireless Rechargeable Implanted Na‐ion Battery for Temporary Medical Devices
Advanced Functional Materials, EarlyView.An all‐solid‐state bioresorbable Na‐ion battery is developed, composed entirely of bio‐eliminable materials. In vivo and ex vivo tests confirmed harmless disintegration of this implanted battery. Lifetime of the implanted battery can be precisely controlled by adjusting the dissolvable encapsulation layer's thickness.
Vedi Kuyil Azhagan Muniraj +8 more
wiley +1 more source