Results 121 to 130 of about 2,564,857 (374)

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Neural networks for small scale ORC optimization [PDF]

, 2017
This study concerns a thermodynamic and technical optimization of a small scale Organic Rankine Cycle system for waste heat recovery applications. An Artificial Neural Network (ANN) has been used to develop a thermodynamic model to be used for the ...
Massimiani, Alessandro, Palagi, Laura, Sciubba, Enrico, Tocci, Lorenzo   +3 more
core   +1 more source

Robocasting of a Water‐Based Biopolymer/WO3 Nanopowder Paste as a Precursor to Tungsten Carbide Lattices

Advanced Engineering Materials, EarlyView.
This study demonstrates a novel, additive manufacturing approach to produce complex, porous tungsten carbide structures using water‐based direct ink writing/robocasting. Leveraging a modified commercial printer and heat treatment, the process yields lightweight, electrically conductive 3D architectures capable of supporting a mechanical load.
James Bentley Bevis, Manasi Shah, Sanketh Gombi, Rodrigo Martinez‐Duarte   +3 more
wiley   +1 more source

Dissecting Causal Links Between Gut Microbiota, Inflammatory Cytokines, and Parkinson's Disease: A Mendelian Randomization Study

Brain and Behavior
Background The association between gut microbiota (GM) and Parkinson's disease (PD) has been well established, but whether there is a causal relationship between the two and whether inflammatory cytokines (ICs) act as mediators remain unclear.
Ma Caiyun, Wen Hebao, Ye Wenhao, Liu Changqing, Li Changqing, Zhao Xiaojiang   +5 more
doaj   +1 more source

Subthalamic hGAD65 Gene Therapy and Striatum TH Gene Transfer in a Parkinson’s Disease Rat Model

Neural Plasticity, 2013
The aim of the present study is to detect a combination method to utilize gene therapy for the treatment of Parkinson’s disease (PD). Here, a PD rat model is used for the in vivo gene therapy of a recombinant adeno-associated virus (AAV2) containing a ...
Deyu Zheng, Xiaohua Jiang, Junpeng Zhao, Deyi Duan, Huanying Zhao, Qunyuan Xu   +5 more
doaj   +1 more source

PORCN Negatively Regulates AMPAR Function Independently of Subunit Composition and the Amino-Terminal and Carboxy-Terminal Domains of AMPARs

Frontiers in Cell and Developmental Biology, 2020
Most fast excitatory synaptic transmissions in the mammalian brain are mediated by α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors (AMPARs), which are ligand-gated cation channels.
Mengping Wei, Mengping Wei, Meng Wang, Jue Wang, Feng Su, Feng Su, Yangzhen Wang, Yangzhen Wang, Meng Sun, Shanshan Wang, Shanshan Wang, Mengna Liu, Mengna Liu, Hongyi Wang, Mingyang Lu, Wei Li, Yutian Gong, Lei Yang, Chen Zhang, Chen Zhang   +19 more
doaj   +1 more source

Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo. [PDF]

, 2009
BackgroundProstate stem/progenitor cells function in glandular development and maintenance. They may be targets for tumor initiation, so characterization of these cells may have therapeutic implications.
Garraway, Isla P, Goldstein, Andrew S, Hahm, Scott A, Haider, Maahum, Head, Christian S, Perner, Sven, Reiter, Robert E, Rubin, Mark A, Sun, Wenyi, Tran, Chau P, Witte, Owen N, Zhang, Bao   +11 more
core   +1 more source

Potential Roles of Dental Pulp Stem Cells in Neural Regeneration and Repair

Stem Cells International, 2018
This review summarizes current advances in dental pulp stem cells (DPSCs) and their potential applications in the nervous diseases. Injured adult mammalian nervous system has a limited regenerative capacity due to an insufficient pool of precursor cells ...
Lihua Luo, Yan He, Xiaoyan Wang, B. Key, B. Lee, Huaqiong Li, Qingsong Ye   +6 more
semanticscholar   +1 more source

Neural Ablation and Regeneration in Pain Practice

The Korean Journal of Pain, 2016
A nerve block is an effective tool for diagnostic and therapeutic methods. If a diagnostic nerve block is successful for pain relief and the subsequent therapeutic nerve block is effective for only a limited duration, the next step that should be considered is a nerve ablation or modulation.
Ju Yeon Kim, Yun Mi Choi, Eun-Ji Choi, Tae Kyun Kim, Kyung-Hoon Kim, Eun Jung Jang   +5 more
openaire   +3 more sources

Advancing Wildfire‐Retardant Materials: Engineering Strategies for Direct and Indirect Suppression

Advanced Engineering Materials, EarlyView.
Here, the evolution, ecological impact, and performance of current fire‐retardant materials and suppression strategies are reviewed, offering an engineering perspective to address existing challenges and propose pathways for the development of more effective, scalable, and sustainable solutions to meet the demands of a changing climate. Wildfires cause
Changxin Dong, Samya Sen, Athena Kolli, Stewart G. Wilson, Eric Andrew Appel   +4 more
wiley   +1 more source