Results 141 to 150 of about 2,564,857 (374)

Chromatin accessibility dynamics and single cell RNA-Seq reveal new regulators of regeneration in neural progenitors

open access: yeseLife, 2020
Vertebrate appendage regeneration requires precisely coordinated remodeling of the transcriptional landscape to enable the growth and differentiation of new tissue, a process executed over multiple days and across dozens of cell types.
A. Kakebeen   +4 more
semanticscholar   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

Germline Transgenic Methods for Tracking Cells and Testing Gene Function During Regeneration in the Axolotl

open access: yes, 2013
The salamander is the only tetrapod that regenerates complex body structures throughout life. Deciphering the underlying molecular processes of regeneration is fundamental for regenerative medicine and developmental biology, but the model organism had ...
Khattak, Shahryar   +9 more
core   +3 more sources

The development of a ε-polycaprolactone (PCL) scaffold for CNS repair [PDF]

open access: yes, 2012
Potential treatment strategies for the repair of spinal cord injury (SCI) currently favour a combinatorial approach incorporating several factors, including exogenous cell transplantation and biocompatible scaffolds. The use of scaffolds for bridging the
Gelain F.   +9 more
core   +1 more source

Eco‐Fabricated Nanowave‐Textured Implants Drive Microtubule‐Assisted Nuclear Mechanotransduction and Chromatin Modification: Biophysical Priming for Osteogenesis and Bone Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
Eco‐friendly nanowave‐textured implants produced via femtosecond laser fabrication enhance bone regeneration by orchestrating a precise mechanotransduction cascade. This nanotopography directs mesenchymal stem cell alignment and cytoskeletal organization, triggering changes in nuclear shape and chromatin acetylation that prime cells for osteogenesis ...
Bosu Jeong   +15 more
wiley   +1 more source

Learning Deep Belief Networks from Non-Stationary Streams

open access: yes, 2012
Deep learning has proven to be beneficial for complex tasks such as classifying images. However, this approach has been mostly applied to static datasets.
Calandra, R   +3 more
core   +1 more source

Modelling of a post-combustion CO₂ capture process using neural networks [PDF]

open access: yes, 2015
This paper presents a study of modelling post-combustion CO₂ capture process using bootstrap aggregated neural networks. The neural network models predict CO₂ capture rate and CO₂ capture level using the following variables as model inputs: inlet flue ...
Li, Fei   +3 more
core   +1 more source

Neural Stimulation and Molecular Mechanisms of Plasticity and Regeneration: A Review

open access: yesFrontiers in Cellular Neuroscience, 2020
Neural stimulation modulates the depolarization of neurons, thereby triggering activity-associated mechanisms of neuronal plasticity. Activity-associated mechanisms in turn play a major role in post-mitotic structure and function of adult neurons.
Matthew K. Hogan   +2 more
semanticscholar   +1 more source

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

open access: yesAdvanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er   +8 more
wiley   +1 more source

Adipose Stem Cell-Based Clinical Strategy for Neural Regeneration: A Review of Current Opinion

open access: yesStem Cells International, 2019
Nerve injury is a critical problem in the clinic. Nerve injury causes serious clinic issues including pain and dysfunctions for patients. The disconnection between damaged neural fibers and muscles will result in muscle atrophy in a few weeks if no ...
Yu-hao Wang   +4 more
semanticscholar   +1 more source

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