Results 151 to 160 of about 213,330 (331)

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

Advanced Healthcare Materials, EarlyView.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez, Adrián Seijas‐Gamardo, Antonio J. Feliciano, Panagiota Kakni, Anna M. Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B. Baker, Lorenzo Moroni   +8 more
wiley   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Foreign body responses in central nervous system mimic natural wound responses and alter biomaterial functions [PDF]

, 2019
Biomaterials hold promise for diverse therapeutic applications in the central nervous system (CNS). Little is known about molecular factors that determine CNS foreign body responses (FBRs) in vivo , or about how such responses influence biomaterial ...
Ao, Yan, Deming, Timothy, Kim, Jae, O’Shea, Timothy, Sofroniew, Michael, Wollenberg, Alexander   +5 more
core   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Grey Box Modeling of a Packed-Bed Regenerator Using Recurrent Neural Networks

, 2019
Verena Halmschlager, Martin Koller, Felix Birkelbach, René Hofmann   +3 more
openalex   +1 more source

Author response for "Transplantation of bioengineered Reelin‐loaded PLGA / PEG micelles can accelerate neural tissue regeneration in photothrombotic stroke model of mouse"

, 2021
Zahra Dehghan Shabani, Reza Rahbarghazi‬, Mohammad Karimipour, Tahereh Ghadiri, Roya Salehi, Saeed Sadigh‐Eteghad, Mehdi Farhoudi   +6 more
openalex   +1 more source

Nanomaterials for neural regeneration

, 2016
Chapter 3 The central nervous system (CNS) consists of a dense network of cells leaving a smaller volume for the extracellular matrix (ECM) components (10‐20% for the brain unlike most other tissues (Cragg, 1979)). The reaction of the nervous tissue to any injury leading to scar tissue formation acts as a barrier for regeneration in the CNS, while it ...
Sever, Melike, Mammadov, Büşra, Geçer, Mevhibe, Güler, Mustafa O., Tekinay, Ayşe B.   +4 more
openaire   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Advances in adhesion interfaces of peripheral nerve repair materials: mechanism, classification, evaluation method, and functionalization

Frontiers in Cell and Developmental Biology
Peripheral nerve injury is a prevalent clinical disease, but achieving functional recovery remains a significant research challenge. In recent years, the therapeutic efficacy of nerve repair materials has garnered widespread attention from researchers ...
Qi Meng, Qi Meng, Qi Meng, Qi Meng, Meng Zhang, Meng Zhang, Meng Zhang, Meng Zhang, Yichong Zhang, Yichong Zhang, Yichong Zhang, Yichong Zhang, Haoran Jiang, Haoran Jiang, Haoran Jiang, Haoran Jiang, Yang Qu, Yang Qu, Yang Qu, Yang Qu, Ci Li, Chenyujun Hu, Chenyujun Hu, Chenyujun Hu, Chenyujun Hu, Zhihao Lin, Zhihao Lin, Zhihao Lin, Zhihao Lin, Bohan Xing, Bohan Xing, Bohan Xing, Bohan Xing, Fengxue Zhu, Peixun Zhang, Peixun Zhang, Peixun Zhang, Peixun Zhang, Peixun Zhang   +38 more
doaj   +1 more source