Results 311 to 320 of about 1,438,323 (398)

Axonal control of the adult neural stem cell niche.

Cell Stem Cell, 2014
C. Tong, Jiadong Chen, A. Cebrian-Silla, Z. Mirzadeh, K. Obernier, Cristina D. Guinto, L. Tecott, J. García-Verdugo, A. Kriegstein, A. Álvarez-Buylla   +9 more
semanticscholar   +1 more source

Human neural stem cell-derived exosomes activate PINK1/Parkin pathway to protect against oxidative stress-induced neuronal injury in ischemic stroke. [PDF]

J Transl Med
Zhao M, Wang J, Zhu S, Zhang S, Han C, Tan C, Huang Y, Sun Z, Wang L, Liu J.   +9 more
europepmc   +1 more source

α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model

Advanced Science, EarlyView.
A novel midbrain–hindbrain assembloid model demonstrates the spread of α‐synuclein pathology, a hallmark of Parkinson's disease, mimicking Braak's hypothesis. This model reveals how pathology propagates from the hindbrain to the midbrain, inducing synaptic changes and early signs of neuronal vulnerability. It offers an innovative platform for exploring
Gemma Gomez‐Giro, Daniela Frangenberg, Daniela Vega, Alise Zagare, Kyriaki Barmpa, Paul M. A. Antony, Graham Robertson, Rahman Sabahi‐Kaviani, Kristian Haendler, Nathalie Kruse, Florentia Papastefanaki, Rebecca Matsas, Malte Spielmann, Regina Luttge, Jens C. Schwamborn   +14 more
wiley   +1 more source

Histone demethylase inhibitor KDM5-C70 regulates metabolomic and lipidomic programming during an astrocyte differentiation of rat neural stem cell. [PDF]

Sci Rep
Shim M, San TT, Shin B, Lee H, Han SB, Lee DK, Kim HJ.   +6 more
europepmc   +1 more source

ZMYND8 Reads H3K36me2 to Activate CEBPE Transcription and Suppress Multiple Myeloma Progression through the Inhibition of Adaptive UPR Pathways

Advanced Science, EarlyView.
Zinc‐finger MYND‐type‐containing 8 (ZMYND8) activates the transcription of CCAAT/enhancer‐binding protein epsilon by recognizing dimethylation of lysine 36 in histone H3 through its Pro‐Trp‐Trp‐Pro domain, thereby inhibiting adaptive unfolded protein response pathways to suppress the proliferation and invasion of multiple myeloma (MM) cells ...
Jiaxuan Xu, Xiaoqing Dong, Yue Peng, Jie Yan, Peipei Xu, Feiyu Li, Suwen Zhang, Lanxin Chen, Xingjun Meng, Kangning Wang, Mengying Xing, Wenyang Li, David C. S. Huang, Quan Zhao, Bing Chen   +14 more
wiley   +1 more source

Cholinesterase Inhibitor Reveals Synergistic Potential for Neural Stem Cell-Based Therapy in the 5xFAD Mouse Model of Alzheimer's Disease. [PDF]

Biologics
Wu CC, Lee YK, Tsai JK, Su YT, Ho YC, Chu TH, Chen KT, Chang CL, Chen JS.   +8 more
europepmc   +1 more source

Neural Stem Cells: A Potential Source for Remyelination in Neuroinflammatory Disease

, 2003
Lou Brundin, Hjalmar Brismar, Alexandre I. Danilov, Tomas Olsson, Clas B. Johansson   +4 more
openalex   +2 more sources

In‐Depth Cell‐Type‐Specific Proteome Landscape of the Brain from Human Amyloid‐β Overexpression Mouse Model

Advanced Science, EarlyView.
In situ Cell‐type‐specific proteome Analysis using antibody‐mediated Biotinylation (iCAB) is a method that directly targets and analyzes proteins in specific cell types within tissue. Applied to 5xFAD mice, iCAB identifies ≈8000 cell‐type‐specific proteins, revealing unique pathways in neurons, astrocytes, and microglia.
Taekyung Ryu, Seok‐Young Kim, Thujitha Thuraisamy, Jisu Shin, Yura Jang, Tae‐In Kam, Chan Hyun Na   +6 more
wiley   +1 more source

Neural Stem Cell–Mediated Enzyme/Prodrug Therapy for Glioma: Preclinical Studies

Science Translational Medicine, 2013
K. Aboody, J. Najbauer, M. Metz, M. D’Apuzzo, M. Gutova, A. Annala, T. Synold, L. Couture, S. Blanchard, R. Moats, Elizabeth Garcia, Soraya Aramburo, V. Valenzuela, Richard T. Frank, M. Barish, Christine E. Brown, Seung U. Kim, B. Badie, J. Portnow   +18 more
semanticscholar   +1 more source

Neural stem cell epigenomes and fate bias are temporally coordinated during corticogenesis

Shapira Y, Noack F, Vangelisti S, Chong F, Lifshitz A, Tanay A, Bonev B.   +6 more
europepmc   +1 more source