Results 311 to 320 of about 1,045,843 (356)
Some of the next articles are maybe not open access.
Glycobiology of Neural Stem Cells
CNS & Neurological Disorders - Drug Targets, 2006The mammalian central nervous system is organized by a variety of cells, such as neurons and glial cells, that are generated from a common progenitor, the neural stem cell (NSC). NSCs are defined as undifferentiated neural cells that are characterized by their high proliferative potential while retaining the capacity for self-renewal and multipotency ...
Makoto Yanagisawa, Robert K. Yu
openaire +2 more sources
Neural stem cell heterogeneity
Progress in Neurobiology, 2018The ‘identity’ of the neural stem cell (NSC) in the adult mammalian brain has captivated the interest and imagination of scientists since the seminal findings in the 1990s revealing the existence of a unique subset of glial-like cells that fulfill the stem cell criteria of self-renewal and multipotentality.
Vincent Tropepe, Jean-Stéphane Joly
openaire +3 more sources
2010
Neural stem cells represent a heterogeneous population of mitotically active, self-renewing and multipotent cells of both the developing and the adult central nervous system (CNS) showing complex patterns of gene expression that may vary in both space and time.
Stefano Pluchino +7 more
openaire +2 more sources
Neural stem cells represent a heterogeneous population of mitotically active, self-renewing and multipotent cells of both the developing and the adult central nervous system (CNS) showing complex patterns of gene expression that may vary in both space and time.
Stefano Pluchino +7 more
openaire +2 more sources
Proteomics of neural stem cells
Expert Review of Proteomics, 2008The isolation of neural stem cells from fetal and adult mammalian CNS and the demonstration of functional neurogenesis in adult CNS have offered perspectives for treatment of many devastating hereditary and acquired neurological diseases. Due to this enormous potential, neural stem cells are a subject of extensive molecular profiling studies with a ...
Hana Kovarova +3 more
openaire +3 more sources
The development of neural stem cells
Nature, 2001The discovery of stem cells that can generate neural tissue has raised new possibilities for repairing the nervous system. A rush of papers proclaiming adult stem cell plasticity has fostered the notion that there is essentially one stem cell type that, with the right impetus, can create whatever progeny our heart, liver or other vital organ desires ...
openaire +3 more sources
Neural Stem Cells and Their Manipulation
2006Extracellular signals dictate the biological processes of neural stem cells (NSCs) both in vivo and in vitro. The intracellular response elicited by these signals is dependent on the context in which the signal is received, which in turn is decided by previous and concurrent signals impinging on the cell.
Prithi Rajan, Evan Y. Snyder
openaire +3 more sources
Neural stem cells and cell death
Toxicology Letters, 2004Neural stem cells (NSC) undergo apoptotic cell death as an essential component of neural development. Here, we present the results of our studies on the mechanisms by which NSC undergo cell death in response to neurotoxic insults. As experimental models we used primary culture of adult NSC from the subventricular zone of the rat brain, and the neural ...
E Sleeper +3 more
openaire +2 more sources
The culture of neural stem cells
Journal of Cellular Biochemistry, 2008AbstractA stem cell has three important features. Firstly, the ability of self‐renewal: making identical copies of itself. Secondly, multipotency, generating all the major cell lineages of the host tissue (in the case of embryonic stem cells—pluripotency). Thirdly, the ability to generate/regenerate tissues.
openaire +2 more sources
2005
Abstract Neural stem cells are a key requirement for neurogenesis to occur. Brain development originates from neuroepithelial stem cells in the neural tube. In the adult brain, in contrast, a population of neural stem cells with glia-like properties is conserved in the walls of the lateral ventricle, driving adult neurogenesis in the ...
openaire +1 more source
Abstract Neural stem cells are a key requirement for neurogenesis to occur. Brain development originates from neuroepithelial stem cells in the neural tube. In the adult brain, in contrast, a population of neural stem cells with glia-like properties is conserved in the walls of the lateral ventricle, driving adult neurogenesis in the ...
openaire +1 more source
Neural Stem Cells and Their Plasticity [PDF]
, 2003 Stem cells are functional units in both development and tissue homeostasis and can be found in a variety of embryonic and adult mammalian tissues. These cells are thought to arise from totipotent embryonic stem (ES) cells of the inner cell mass of the blastocyst from which distinct groups of precursors segregate into the three main germ layers ...
Rossella Galli +2 more
openaire +1 more source