Results 201 to 210 of about 32,363 (291)

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

ARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans. [PDF]

Genome Biol
Luo H, Lao L, Au KS, Northrup H, He X, Forget D, Gauthier MS, Coulombe B, Bourdeau I, Shi W, Gagliardi L, Fragoso MCBV, Peng J, Wu J.   +13 more
europepmc   +1 more source

Functional Validation of CLDN Variants Identified in a Neural Tube Defect Cohort Demonstrates Their Contribution to Neural Tube Defects. [PDF]

Front Neurosci, 2020
Baumholtz AI, De Marco P, Capra V, Ryan AK.   +3 more
europepmc   +1 more source

COMPUTATIONAL ANALYSIS OF INTERACTIONS BETWEEN ANTI-EPILEPTIC DRUGS AND IMPORTANT PLACENTAL PROTEINS-A POSSIBLE ROUTE FOR NEURAL TUBE DEFECTS IN HUMANS

, 2016
Santhanam Vijayasri, Hari Archana, Arvind Agrawal, Waheeta Hopper   +3 more
openalex   +1 more source

Maternal Subcutaneous Seroma Following Open Maternal Fetal Surgery for Closure of Fetal Open Neural Tube Defects [PDF]

Desiree Fiorentino, Christina Paidas Teefey, Shelly Soni, Nahla Khalek, Alekhya Jampa, Gregory G. Heuer, Alan W. Flake, Holly L. Hedrick, William H. Peranteau, N. Scott Adzick, Julie S. Moldenhauer, Juliana Gebb   +11 more
openalex   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

EXAMINATION OF CBP/P300/AKT, NF-ΚB AND STAT3 SIGNALING FOLLOWING IN UTERO VALPROIC ACID EXPOSURE IN CD-1 MOUSE EMBRYOS WITH NEURAL TUBE DEFECTS

, 2020
Sidra Shafique
openalex   +1 more source

Neural tube defects: Risk factors and preventive measures [PDF]

, 2017
Atsuo Kondo, Takuya Matsuo, Nobuhito Morota, Atsuya Kondo, Ikuyo Okai, Hiromi Fukuda, Ikuyo Okai, Hiromi Fukuda   +7 more
openalex   +1 more source

Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain

Advanced Science, EarlyView.
ABSTRACT The blood‐brain barrier (BBB) renders the delivery of nanomedicine in the brain ineffective and the detection of circulating disease‐related DNA from the brain unreliable. Here, we demonstrate that microbubble‐enhanced focused ultrasound (MB‐FUS) mediated BBB opening, supported by large‐data models predict sonication regimens for safe and ...
Hohyun Lee, Victor Menezes, Shiqin Zeng, Chulyong Kim, Cynthia M. Baseman, Jae Hyun Kim, Samhita Padmanabhan, Pranav Premdas, Naima Djeddar, Anton Bryksin, Nikhil Pandey, Pavlos Anastasiadis, Anthony J. Kim, Tobey J. MacDonald, Chetan Bettegowda, Graeme F. Woodworth, Felix J. Herrmann, Costas Arvanitis   +17 more
wiley   +1 more source

miR-322 treatment rescues cell apoptosis and neural tube defect formation through silencing NADPH oxidase 4. [PDF]

CNS Neurosci Ther, 2020
Liu YS, Gu H, Huang TC, Wei XW, Ma W, Liu D, He YW, Luo WT, Huang JT, Zhao D, Jia SS, Wang F, Zhang T, Bai YZ, Wang WL, Yuan ZW.   +15 more
europepmc   +1 more source