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Neural Tube Defects [PDF]

open access: yesPediatric Neurology Briefs, 1988
In an overview of neural tube defects (NTD’s), Dr RJ Lemire of the Dept Pediatrics, Univ of Washington and Children’s Hospital, Seattle, WA, divides them into two major groups: (1) neurulation and (2) postneurulation defects.
J Gordon Millichap
doaj   +6 more sources

Neural tube defects

open access: yesCurationis, 1981
Neural tube defects refer to any defect in the morphogenesis of the neural tube, the most common types being spina bifida and anencephaly. Spina bifida has been recognised in skeletons found in north-eastern Morocco and estimated to have an age of almost
M.E. Marshall
doaj   +4 more sources

Folic acid supplementation and neural tube defects: a cross-sectional study of knowledge and practice among pregnant mothers in Lira, Northern Uganda [PDF]

open access: yesBMC Pregnancy and Childbirth
Background and aim Folic acid requirements increase during pregnancy to meet the metabolic needs, DNA synthesis, and rapid cell division during fetal development.
Rebecca Nakaziba, Miriam Muhindo
doaj   +2 more sources

Birth prevalence of neural tube defects and orofacial clefts in India: a systematic review and meta-analysis.

open access: yesPLoS ONE, 2015
BackgroundIn the last two decades, India has witnessed a substantial decrease in infant mortality attributed to infectious disease and malnutrition. However, the mortality attributed to birth defects remains constant.
Komal Preet Allagh   +7 more
doaj   +3 more sources

Trend and burden of neural tube defects among cohort of pregnant women in Ethiopia: Where are we in the prevention and what is the way forward?

open access: yesPLoS ONE, 2022
Introduction Neural tube defect is one of the top five most serious birth defects in the world. In Ethiopia an accurate estimate of the trend and burden of neural tube defects is still unknown.
Anteneh Berhane, Tefera Belachew
doaj   +3 more sources

Neural tube defects [PDF]

open access: yesCanadian Medical Association Journal, 2005
Although Joel Ray and associates[1][1] may have adequately controlled for confounding in their study of neural tube defects among children born in Ontario, the study may suffer from bias in data collection, analysis and interpretation, and the conclusions drawn may therefore be premature.
Fu-Lin, Wang   +2 more
openaire   +5 more sources

Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development

open access: yesFrontiers in Cell and Developmental Biology, 2023
Neural tube closure is a fundamental process during vertebrate embryogenesis, which leads to the formation of the central nervous system. Defective neural tube closure leads to neural tube defects which are some of the most common human birth defects ...
Neophytos Christodoulou   +1 more
doaj   +1 more source

Neural Tube Defects [PDF]

open access: yesAnnual Review of Neuroscience, 2014
Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth defects of the central nervous system that originate during embryonic development when the neural tube fails to close completely. Human NTDs are multifactorial, with contributions from both genetic and environmental factors. The genetic basis is not yet well understood,
Greene, ND, Copp, AJ
openaire   +3 more sources

A quest for genetic causes underlying signaling pathways associated with neural tube defects

open access: yesFrontiers in Pediatrics, 2023
Neural tube defects (NTDs) are serious congenital deformities of the nervous system that occur owing to the failure of normal neural tube closures. Genetic and non-genetic factors contribute to the etiology of neural tube defects in humans, indicating ...
Sunil Rai   +4 more
doaj   +1 more source

Thoracic and lumbar multiple neural tube defects with post repair hydrocephalus: A case report and literature review

open access: yesInterdisciplinary Neurosurgery, 2023
Background: Neural tube defects are among the most common congenital anomalies, particularly in developing countries owing to significant folic acid deficiency. Nevertheless, multiple-site open neural tube defects are extremely rare.
Eyerusalem Bergene   +3 more
doaj   +1 more source

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