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Pediatric Neurology Briefs, 1988 In an overview of neural tube defects (NTD’s), Dr RJ Lemire of the Dept Pediatrics, Univ of Washington and Children’s Hospital, Seattle, WA, divides them into two major groups: (1) neurulation and (2) postneurulation defects.
J Gordon Millichap
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Curationis, 1981 Neural tube defects refer to any defect in the morphogenesis of the neural tube, the most common types being spina bifida and anencephaly. Spina bifida has been recognised in skeletons found in north-eastern Morocco and estimated to have an age of almost
M.E. Marshall
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Epidemiology of Neural Tube Defects [PDF]
Epilepsia, 2003 Summary: Neural tube defects (NTDs)—malformations secondary to abnormal neural tube closure between the third and fourth weeks of gestational age—have a complex and imperfectly understood etiology in which both genetic and environmental factors appear to be involved.
Lauren Frey, W Allen Hauser
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Cell Reports, 2019 Summary: Neural tube defects (NTDs) are common birth defects in humans and show an unexplained female bias. Female mice lacking the tumor suppressor p53 display NTDs with incomplete penetrance. We found that the combined loss of pro-apoptotic BIM and p53
Alex R.D. Delbridge +21 more
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Folic acid supplementation and neural tube defects: a cross-sectional study of knowledge and practice among pregnant mothers in Lira, Northern Uganda [PDF]
BMC Pregnancy and ChildbirthBackground and aim Folic acid requirements increase during pregnancy to meet the metabolic needs, DNA synthesis, and rapid cell division during fetal development.
Rebecca Nakaziba, Miriam Muhindo
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PLoS ONE, 2015 BackgroundIn the last two decades, India has witnessed a substantial decrease in infant mortality attributed to infectious disease and malnutrition. However, the mortality attributed to birth defects remains constant.
Komal Preet Allagh +7 more
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PLoS ONE, 2022 Introduction Neural tube defect is one of the top five most serious birth defects in the world. In Ethiopia an accurate estimate of the trend and burden of neural tube defects is still unknown.
Anteneh Berhane, Tefera Belachew
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Canadian Medical Association Journal, 2005 Although Joel Ray and associates[1][1] may have adequately controlled for confounding in their study of neural tube defects among children born in Ontario, the study may suffer from bias in data collection, analysis and interpretation, and the conclusions drawn may therefore be premature.
Fu-Lin, Wang +2 more
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Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development
Frontiers in Cell and Developmental Biology, 2023 Neural tube closure is a fundamental process during vertebrate embryogenesis, which leads to the formation of the central nervous system. Defective neural tube closure leads to neural tube defects which are some of the most common human birth defects ...
Neophytos Christodoulou +1 more
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Annual Review of Neuroscience, 2014 Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth defects of the central nervous system that originate during embryonic development when the neural tube fails to close completely. Human NTDs are multifactorial, with contributions from both genetic and environmental factors. The genetic basis is not yet well understood,
Greene, ND, Copp, AJ
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