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Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth defects of the central nervous system that originate during embryonic development when the neural tube fails to close completely.
Copp, AJ, Greene, ND
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Neural tube defects refer to any defect in the morphogenesis of the neural tube, the most common types being spina bifida and anencephaly. Spina bifida has been recognised in skeletons found in north-eastern Morocco and estimated to have an age of almost
M.E. Marshall
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In an overview of neural tube defects (NTD’s), Dr RJ Lemire of the Dept Pediatrics, Univ of Washington and Children’s Hospital, Seattle, WA, divides them into two major groups: (1) neurulation and (2) postneurulation defects.
J Gordon Millichap
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The population-based study of neural tube defects by Joel Ray and associates[1][1] raises 2 important concerns. First, as noted by the authors in their discussion of study limitations, ethnicity may simply be a confounding factor in neural tube defects caused by poor folic acid intake. Second,
Fu-Lin, Wang +2 more
+11 more sources
Junctional Neural Tube Defect [PDF]
Junctional neurulation represents the most recent adjunct to the well-known sequential embryological processes of primary and secondary neurulation. While its exact molecular processes, occurring at the end of primary and the beginning of secondary neurulation, are still being actively investigated, its pathological counterpart -junctional neural tube ...
Sebastian Eibach, Dachling Pang
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Neural tube defects (NTDs) are the most common congenital malformations (CMFs) in developing fetus. The study was done to determine the incidence and clinical profile of NTDs at a tertiary care hospital. The study was done at Malla Reddy Institute of Medical Sciences, Suraram, Hyderabad, from June 2019 to June 2020.
Sowmya Mailaram +4 more
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Demonstration of astrocytes in cultured amniotic fluid cells of three cases with neural-tube defect [PDF]
We have investigated the origin of rapidly adhering (RA) cells in three cases of neural tube defects (two anencephali, one encephalocele). We were able to demonstrate the presence of glial fibrillary acidic (GFA) protein in variable percentages (4–80 ...
AD Smith +18 more
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Introduction: Neural tube defects [PDF]
This volume of Neurosurgical Focus covers an array of topics useful to many specialists who care for patients with neural tube defects and related abnormalities. These patients have specific needs at each stage of the lifespan. Today, many individuals with significant developmental abnormalities of the spinal cord are leading full lives.
Shenandoah, Robinson +3 more
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Involvement of deprivation and environmental lead in neural tube defects:a matched case-control study. [PDF]
OBJECTIVE. To analyse the prevalence of neural tube defects in small geographical areas and seek to explain any spatial variations with reference to environmental lead and deprivation. SETTING.
Awwad, Fuad +4 more
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Failures of neural tube closure are common and serious birth defects, yet we have a poor understanding of the interaction of genetics and cell biology during neural tube closure.
Austin T Baldwin +3 more
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