Results 1 to 10 of about 12,090 (225)

Spinal neural tube formation and tail development in human embryos [PDF]

open access: yeseLife
Primary and secondary neurulation – processes that form the spinal cord – are incompletely understood in humans, largely due to the challenge of accessing neurulation-stage embryos (3–7 weeks post-conception).
Chloe Santos   +9 more
doaj   +2 more sources

Spectral decomposition unlocks ascidian morphogenesis [PDF]

open access: yeseLife
Describing morphogenesis generally consists in aggregating the multiple high-resolution spatiotemporal processes involved into reproducible low-dimensional morphological processes consistent across individuals of the same species or group.
Joel Dokmegang   +4 more
doaj   +2 more sources

Linking planar polarity signalling to actomyosin contractility during vertebrate neurulation [PDF]

open access: yesOpen Biology
Actomyosin contractility represents an ancient feature of eukaryotic cells participating in many developmental and homeostasis events, including tissue morphogenesis, muscle contraction and cell migration, with dysregulation implicated in various ...
Sarka Novotna   +4 more
doaj   +2 more sources

Imaging in Spinal DysraphismA Pictoral Assay [PDF]

open access: yesInternational Journal of Anatomy Radiology and Surgery, 2021
Spinal dysraphism includes the congenital malformations of the spine and spinal cord. Spinal cord development takes place through successive stages of gastrulation, primary neurulation, and secondary neurulation. Defect in any of these three phases can
Anurudh Kishore Vatti   +2 more
doaj   +1 more source

Mitochondria in Early Forebrain Development: From Neurulation to Mid-Corticogenesis

open access: yesFrontiers in Cell and Developmental Biology, 2021
Function of the mature central nervous system (CNS) requires a substantial proportion of the body’s energy consumption. During development, the CNS anlage must maintain its structure and perform stage-specific functions as it proceeds through discrete ...
Ryann M. Fame, Maria K. Lehtinen
doaj   +1 more source

Vangl2–environment interaction causes severe neural tube defects, without abnormal neuroepithelial convergent extension

open access: yesDisease Models & Mechanisms, 2022
Planar cell polarity (PCP) signalling is vital for initiation of mouse neurulation, with diminished convergent extension (CE) cell movements leading to craniorachischisis, a severe neural tube defect (NTD).
Oleksandr Nychyk   +6 more
doaj   +1 more source

Case series of cranial and spinal dysraphism

open access: yesNational Journal of Clinical Anatomy, 2022
Neural tube defects (NTDs) are the second most common cause of congenital anomaly worldwide (cardiac anomalies is the first). The 3rd and 4th week of gestation is the critical period for neural tube development. Multiple genetic and environmental factors
Gayathri Pandurangam   +3 more
doaj   +1 more source

Spinal Dysraphisms: A New Anatomical–Clinicoradiological Classification

open access: yesIndian Journal of Radiology and Imaging, 2021
Background Spinal dysraphisms refer to the congenital abnormalities of the spine and spinal cord due to aberrations in the processes of gastrulation, primary neurulation, and secondary neurulation. Embryology of many complex spinal dysraphisms
Amarnath Chellathurai   +4 more
doaj   +1 more source

Cannibalized erythroblasts accelerate developmental neurogenesis by regulating mitochondrial dynamics

open access: yesCell Reports, 2021
Summary: Metabolic support was long considered to be the only developmental function of hematopoiesis, a view that is gradually changing. Here, we disclose a mechanism triggered during neurulation that programs brain development by donation of ...
Şükran Özsoy   +5 more
doaj   +1 more source

Altered Glutaminase 1 Activity During Neurulation and Its Potential Implications in Neural Tube Defects

open access: yesFrontiers in Pharmacology, 2020
The neurulation process is regulated by a large amount of genetic and environmental factors that determine the establishment, folding, and fusion of the neural plate to form the neural tube, which develops into the main structure of the central nervous ...
Camila Benavides-Rivas   +11 more
doaj   +1 more source

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