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Fold-and-fuse neurulation in zebrafish requires vangl2. [PDF]
Dev Biol, 2023 Abstract Shaping of the future brain and spinal cord during neurulation is an essential component of early vertebrate development. In amniote embryos, primary neurulation occurs through a “fold-and-fuse” mechanism by which the edges of the neural plate fuse into the hollow neural tube.
MacGowan J, Cardenas M, Williams MK.
europepmc +5 more sources
Mitochondria in Early Forebrain Development: From Neurulation to Mid-Corticogenesis
Frontiers in Cell and Developmental Biology, 2021 Function of the mature central nervous system (CNS) requires a substantial proportion of the body’s energy consumption. During development, the CNS anlage must maintain its structure and perform stage-specific functions as it proceeds through discrete ...
Maria Lehtinen, Ryann Fame
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Ivermectin exposition during neurulation induces neural tube defects and neuromuscular alterations in Xenopus laevis through purinergic P2X4-signaling [PDF]
Frontiers in PharmacologyBackgroundNeurulation is a fundamental process in the formation of the central nervous system (CNS). The process begins with the folding and fusion of the neural plate to form the neural tube which subsequently gives rise to the development of the brain ...
Claudio Catrupay-Valdebenito +8 more
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Frontiers in Pharmacology, 2020 The neurulation process is regulated by a large amount of genetic and environmental factors that determine the establishment, folding, and fusion of the neural plate to form the neural tube, which develops into the main structure of the central nervous ...
Luisa Bascuñán +2 more
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Quantitative live imaging reveals PRICKLE1 controls junctional neural tube morphogenesis independent of Planar Cell Polarity [PDF]
Nature CommunicationsNeurulation, the process that forms the neural tube - the precursor to the brain and spinal cord - is frequently disrupted in congenital malformations.
Jian Xiong Wang +5 more
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Spinal neural tube formation and tail development in human embryos [PDF]
eLifePrimary and secondary neurulation – processes that form the spinal cord – are incompletely understood in humans, largely due to the challenge of accessing neurulation-stage embryos (3–7 weeks post-conception).
Chloe Santos +9 more
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Hemichordate neurulation and the origin of the neural tube [PDF]
Nature Communications, 2013 The origin of the body plan of our own phylum, Chordata, is one of the most fascinating questions in evolutionary biology. Yet, after more than a century of debate, the evolutionary origins of the neural tube and notochord remain unclear. Here we examine the development of the collar nerve cord in the hemichordate Balanoglossus simodensis and find ...
Norio Miyamoto, Hiroshi Wada
exaly +3 more sources
Imaging in Spinal DysraphismA Pictoral Assay [PDF]
International Journal of Anatomy Radiology and Surgery, 2021 Spinal dysraphism includes the congenital malformations of the spine and spinal cord. Spinal cord development takes place through successive stages of gastrulation, primary neurulation, and secondary neurulation. Defect in any of these three phases can
Anurudh Kishore Vatti +2 more
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Classification of Spinal Lipomas Based on Embryonic stage: Overview and Case Series [PDF]
Pan Arab Journal of Neurosurgery, 2021 BACKGROUND: Unsuccessful primary neurulation is usually considered to be the main origin of spinal lipomatous malformations. Yet, we are not able to clarify many of its characteristics using this hypothesis.
Hesham Habba, Tariq Awad
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Spinal Dysraphisms: A New Anatomical–Clinicoradiological Classification
Indian Journal of Radiology and Imaging, 2021 Background Spinal dysraphisms refer to the congenital abnormalities of the spine and spinal cord due to aberrations in the processes of gastrulation, primary neurulation, and secondary neurulation. Embryology of many complex spinal dysraphisms
Amarnath Chellathurai +4 more
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