Results 41 to 50 of about 5,306 (135)

Embryopathological relationship between retained medullary cord and caudal spinal lipoma

open access: yesInterdisciplinary Neurosurgery, 2022
Purpose: Retained medullary cord (RMC) is a condition in which the cord-like structure (C-LS) is continuous from the conus and extends to the dural cul-de-sac, causing spinal cord tethering, which is thought to originate from the secondary neurulation ...
Takato Morioka   +7 more
doaj   +1 more source

Complete surgical excision of a type V‐variant dermoid sinus (V/VI overlap) associated with spina bifida in a Shiba Inu dog: A case report

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To describe the clinical, imaging, surgical, and histopathologic features of a type V/VI overlap dermoid sinus (DS), and highlight diagnostic and therapeutic considerations. Study design Case report. Animal A 16‐month‐old spayed female Shiba Inu dog.
Ji‐Eun Jeong   +2 more
wiley   +1 more source

Developmental Trajectory of Auditory Brainstem Deficits in a Mouse Model of Fetal Alcohol Spectrum Disorders

open access: yesDevelopmental Neurobiology, Volume 86, Issue 4, October 2026.
ABSTRACT Individuals with fetal alcohol spectrum disorders exhibit impaired auditory processing and atypical auditory behaviors across the disorder's spectrum. Although low to moderate prenatal alcohol exposure (PAE) is a prevalent type of exposure, the developmental trajectory of auditory processing deficits resulting from this level of exposure ...
Michael Douchey   +3 more
wiley   +1 more source

RETRACTED ARTICLE: Functional cargos of exosomes derived from Flk-1+ vascular progenitors enable neurulation and ameliorate embryonic anomalies in diabetic pregnancy

open access: yesCommunications Biology, 2022
Various types of progenitors initiate individual organ formation and their crosstalk orchestrates morphogenesis for the entire embryo. Here we show that progenitor exosomal communication across embryonic organs occurs in normal development and is altered
Songying Cao   +6 more
doaj   +1 more source

Innovative Methods for Prenatal Cannabis Exposure: Vapor Inhalation Chamber and Metabolite Quantification in Prairie Voles and Rats

open access: yesDevelopmental Psychobiology, Volume 68, Issue 4, July 2026.
ABSTRACT The increasing prevalence of cannabis use, including among pregnant women, highlights the critical need for a deeper understanding of prenatal cannabis exposure. This study aimed to develop a standardized cross‐species inhalation exposure protocol to administer the principal psychoactive component of cannabis, Δ9‐tetrahydrocannabinol (THC), to
Sophia Rogers   +10 more
wiley   +1 more source

miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability

open access: yesCell Reports, 2015
The evolutionarily conserved miR-302 family of microRNAs is expressed during early mammalian embryonic development. Here, we report that deletion of miR-302a-d in mice results in a fully penetrant late embryonic lethal phenotype. Knockout embryos have an
Ronald J. Parchem   +9 more
doaj   +1 more source

A Combination of Variants in SEPTIN9 and MSX1 Genes Leads to the Formation of Orofacial Clefts

open access: yesGenes to Cells, Volume 31, Issue 4, July 2026.
Double‐depleted Xenopus embryos of xMSX1 and xSEPTIN9 exhibited orofacial clefts, and wild‐type but not variants in human MSX1 and human SEPTIN9 mRNAs could rescue the phenotype of morphants, indicating that variants in MSX1 and SEPTIN9, each individually tolerated, synergistically disrupt craniofacial morphogenesis to cause orofacial clefts.
Udval Uuganbayar   +13 more
wiley   +1 more source

Generation and Characterization of Twist1 Acetyl‐Mimic and Acetyl‐Deficient Mouse Models

open access: yesgenesis, Volume 64, Issue 3, June 2026.
ABSTRACT TWIST1 encodes a highly conserved basic helix–loop–helix transcription factor essential for embryonic development from Drosophila to humans. TWIST1 activity is regulated by post‐translational modifications, including phosphorylation during development and cancer metastasis. Recent cancer studies identified acetylation of lysines K73 and K76 as
Mary Elmeniawi   +6 more
wiley   +1 more source

Spatial omics in the AI era: Technologies, algorithmic ecosystems, biological applications, and large model perspectives

open access: yesiMeta, Volume 5, Issue 3, June 2026.
This review focuses on spatial omics, covering the introduction and comparison of technology platforms, explanation and recommendation of algorithm ecology, demonstration of biological applications, and prospect of large models. It aims to help researchers in the interdisciplinary field of spatial omics quickly understand the current situation and ...
Haoxiu Wang   +26 more
wiley   +1 more source

Progesterone improves the number and quality of hormone induced Fowler toad (Bufo fowleri) oocytes

open access: yesReproductive Biology and Endocrinology, 2006
Combinations of progesterone, lutenizing hormone releasing hormone analogue (LHRHa), human chorionic gonadotrophin (hCG), and the dopamine-2 (DA2) receptor antagonist 1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one ...
Li Hong   +3 more
doaj   +1 more source

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