Results 61 to 70 of about 12,090 (225)

Epithelial fusion during neural tube morphogenesis [PDF]

, 2012
Adhesion and fusion of epithelial sheets marks the completion of many morphogenetic events during embryogenesis. Neural tube closure involves an epithelial fusion sequence in which the apposing neural folds adhere initially via cellular protrusions ...
Abdul-Aziz, Bader, Baudoin, Brouns, Camerer, Cecconi, Chen, Copp, Copp, Copp, Cremer, De Arcangelis, Dravis, Furman, Geelen, George, Glise, Hall, Holmberg, Hong, Hoving, Hynes, Jacinto, Jacinto, Jacobson, Kuan, Larue, Leonard, Martin, Massa, McLaughlin, Menzies, Merrill, Miner, Mirkes, Moase, Murai, Pyrgaki, Pyrgaki, Radice, Ridley, Rifat, Risley, Sabapathy, Schluter, Shimizu, Stephen, Sugihara, Taya, Van Straaten, Vasioukhin, Waterman, Weil, Werth, Weston, Wood, Woolner, Yamaguchi   +57 more
core   +1 more source

Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience

Annals of the Child Neurology Society, Volume 4, Issue 1, Page 15-28, March 2026.
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf, Timothy M. Crombleholme, Leon G. Epstein, Dawn Gano, Phillip L. Pearl, Timothy V. Salomons, Mark S. Scher, Elise Turk, Klaus‐Peter Zimmer, Harvey B. Sarnat   +9 more
wiley   +1 more source

Neural tube defects [PDF]

, 2014
Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth defects of the central nervous system that originate during embryonic development when the neural tube fails to close completely.
Copp, AJ, Greene, ND
core   +1 more source

miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability

Cell Reports, 2015
The evolutionarily conserved miR-302 family of microRNAs is expressed during early mammalian embryonic development. Here, we report that deletion of miR-302a-d in mice results in a fully penetrant late embryonic lethal phenotype. Knockout embryos have an
Ronald J. Parchem, Nicole Moore, Jennifer L. Fish, Jacqueline G. Parchem, Tarcio T. Braga, Archana Shenoy, Michael C. Oldham, John L.R. Rubenstein, Richard A. Schneider, Robert Blelloch   +9 more
doaj   +1 more source

Association between fetal brain diffusion‐weighted imaging and postnatal neurodevelopmental outcome after prenatal myelomeningocele repair

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 3, Page 329-340, March 2026.
ABSTRACT Objective Myelomeningocele (MMC) is associated with significant alterations of the brain microstructure, which can impair long‐term neurodevelopmental outcomes. By measuring the random displacement of water molecules within the brain, magnetic resonance imaging (MRI)‐based diffusion‐weighted imaging (DWI) can provide objective metrics, such as
R. Corroenne, T. A. G. M. Huisman, W. E. Whitehead, A. A. Nassr, J. L. Munoz, J. Castillo, H. Castillo, R. M. Johnson, R. V. Donepudi, M. A. Belfort, M. Sanz‐Cortes   +10 more
wiley   +1 more source

Cell motility driving mediolateral intercalation in explants of Xenopus laevis [PDF]

, 1992
In Xenopus, convergence and extension are produced by active intercalation of the deep mesodermal cells between one another along the mediolateral axis (mediolateral cell intercalation), to form a narrower, longer array.
Keller, Ray, Shih, John
core  

A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico, Irene Chiesa, Angela Toffano, Alessio Esposito, Piera Mancini, Chiara Magliaro, Angeliki Louvi, Carmelo De Maria, Marco Onorati   +8 more
wiley   +1 more source

The epithelium of the dorsal marginal zone of Xenopus has organizer properties [PDF]

, 1992
We have investigated the properties of the epithelial layer of the dorsal marginal zone (DMZ) of the Xenopus laevis early gastrula and found that it has inductive properties similar to those of the entire Spemann organizer.
Keller, Ray, Shih, John
core  

Novel roles of the chemorepellent axon guidance molecule RGMa in cell migration and adhesion [PDF]

, 2012
The repulsive guidance molecule A (RGMa) is a contact-mediated axon guidance molecule that has significant roles in central nervous system (CNS) development.
Aamar E, Babitt JL, Bork P, Brinks H, Camus LM, Cha JY, Colombatti A, Connor RM, Conrad S, Cooke JE, Cousin H, Feys T, Gavert N, Gessert S, Goodeve AC, Goto T, Halbrooks PJ, Karaulanov EE, Kee N, Keller R, Keller R, Keller R, Kidd T, Kondo Y, Kwan KM, Lamb TM, Laurent A, Li J, Li VSW, Louie SH, Matsunaga E, Mawdsley DJ, Millard SS, Mirakaj V, Monnier PP, Muramatsu R, Niederkofler V, Nieuwkoop P, Okamura Y, Oldekamp J, Popsueva AE, Rajagopalan S, Re'em-Kalma Y, Samad TA, Samad TA, Schafer MK, Schmidtmer J, Shiau CE, Shin GJ, Skoglund P, Tardif S, Tassew NG, Tassew NG, Vielmetter J, Wilson NH, Wilson NH, Wojtowicz WM, Xia Y, Zhou Z   +58 more
core   +1 more source

Plate-curving cell culture as a model for assessing curvature-induced cellular responses during neural tube morphogenesis

Animal Cells and Systems, 2023
Neurulation is an important shape-transforming event during embryonic development where a flat neural plate is converted into a neural tube. Failure in this morphogenetic process accounts for one of the most common birth defects.
Hyung-Min Ahn, Woong Sun
doaj   +1 more source