Results 71 to 80 of about 7,028 (158)

Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases

Prenatal Diagnosis, Volume 46, Issue 5-6, Page 849-861, May 2026.
ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei, A. Feresin, R. Zemet, D. Berner, D. Polidori, K. Fröbius, A. Skakkebæk, R. Axt‐Fliedner, M. Shoukier, C. Keil   +9 more
wiley   +1 more source

A rare complex association of dermal sinus tract, dermoid cyst, filum terminale lipoma, tethered spinal cord and syringomyelia: A case report and literature review

Interdisciplinary Neurosurgery
Background: Dermal sinus tract is a rare type of spinal dysraphism. It is usually associated with other types of spinal congenital anomalies. This work shows the rare co-occurrence of primary and secondary neurulation defect in a single patient.
Mekdes Musie Awano, Eyob Zenebe Wendimagegnehu   +1 more
doaj   +1 more source

Neural Tube Defects

Pediatric Neurology Briefs, 1988
In an overview of neural tube defects (NTD’s), Dr RJ Lemire of the Dept Pediatrics, Univ of Washington and Children’s Hospital, Seattle, WA, divides them into two major groups: (1) neurulation and (2) postneurulation defects.
J Gordon Millichap
doaj   +1 more source

The orphan GPCR, Gpr161, regulates the retinoic acid and canonical Wnt pathways during neurulation [PDF]

, 2015
The vacuolated lens (vl) mouse mutation arose on the C3H/HeSnJ background and results in lethality, neural tube defects (NTDs) and cataracts. The vl phenotypes are due to a deletion/frameshift mutation in the orphan GPCR, Gpr161.
Nanda, Vikas, Nato, Alejandro Q., Jr., Nato, Alejandro Q., Matise, Tera C., Matise, Tara C., Matteson, Paul G., Lin, Yong, Li, Bo I., Millonig, James H., Ababon, Myka F.   +9 more
core   +1 more source

Spectral decomposition unlocks ascidian morphogenesis

eLife
Describing morphogenesis generally consists in aggregating the multiple high-resolution spatiotemporal processes involved into reproducible low-dimensional morphological processes consistent across individuals of the same species or group.
Joel Dokmegang, Emmanuel Faure, Patrick Lemaire, Edwin Munro, Madhav Mani   +4 more
doaj   +1 more source

Calcium signaling in tunicate development

Frontiers in Ecology and Evolution
A comparative overview is provided of Ca2+ signaling and its potential mechanistic roles during development in tunicates. As background, the review presents an introduction to tunicate taxonomy, and then a general overview of Ca2+ signaling and methods ...
Joel C. Glover, Joel C. Glover, Oleg Tolstenkov, Yana Mikhaleva   +3 more
doaj   +1 more source

Cell-Autonomous Ca2+ Flashes Elicit Pulsed Contractions of an Apical Actin Network to Drive Apical Constriction during Neural Tube Closure

Cell Reports, 2015
Neurulation is a critical period in all vertebrates and results in the formation of the neural tube, which gives rise to the CNS. Apical constriction is one of the fundamental morphogenetic movements that drives neural tube closure.
Neophytos Christodoulou, Paris A. Skourides   +1 more
doaj   +1 more source

Linking planar polarity signalling to actomyosin contractility during vertebrate neurulation

Open Biology
Actomyosin contractility represents an ancient feature of eukaryotic cells participating in many developmental and homeostasis events, including tissue morphogenesis, muscle contraction and cell migration, with dysregulation implicated in various ...
Sarka Novotna, Lorena Agostini Maia, Katarzyna Anna Radaszkiewicz, Pavel Roudnicky, Jakub Harnos   +4 more
doaj   +1 more source

Actin Distribution in Lamina Neuralis During Cranial Neurulation of Wistar Rats Embryo (Rattus rattus)

Indonesian Journal of Biotechnology, 2008
such as craniorachisis and exencephaly. One of the processes is changing in lamina neuralis cells shape, which is caused by actin microfilament rearrangement within lamina neuralis cells.
Indriayuni Prahastuti, S.M. Issoegianti R.   +1 more
doaj   +1 more source

Surgical and Non-Surgical Outcome of Asymptomatic Lumbosacral Lipomas in Children: A Systematic Review

Clinical and Translational Neuroscience
Background: The management of asymptomatic lumbosacral lipomas remains controversial, with studies reporting both prophylactic surgery and conservative management.
Nazar S. Annanepesov, Justina Phiri, Gennady E. Chmutin, Gerald Musa, Nicola Montemurro   +4 more
doaj   +1 more source