Advanced Science, Volume 13, Issue 8, 9 February 2026.Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li +3 more
wiley +1 more source
Teratogenic effects of gabapentin on neural tube and limb development in mice [PDF]
, 2008 [No abstract ...
Afshar, M., Golalipour, M.J.
core
Mechanical shock during egg de-adhesion and post-ovulatory ageing contribute to spontaneous autopolyploidy in white sturgeon culture (Acipenser transmontanus) [PDF]
, 2020 Spontaneous autopolyploidy, a 1.5x increase in genome size resulting from second polar body retention after fertilization, has been documented in cultured sturgeons, with the proportion of spontaneous autopolyploid progeny ranging widely among maternal ...
Conte, FS +6 more
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Progesterone improves the number and quality of hormone induced Fowler toad (
Reproductive Biology and Endocrinology, 2006 Combinations of progesterone, lutenizing hormone releasing hormone analogue (LHRHa), human chorionic gonadotrophin (hCG), and the dopamine-2 (DA2) receptor antagonist 1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one ...
Li Hong +3 more
doaj +1 more source
Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling
Brain and Behavior, Volume 16, Issue 2, February 2026.Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu +1 more
wiley +1 more source
Suv4-20h Histone Methyltransferases Promote Neuroectodermal Differentiation by Silencing the Pluripotency-Associated Oct-25 Gene [PDF]
, 2013 Post-translational modifications (PTMs) of histones exert fundamental roles in regulating gene expression. During development, groups of PTMs are constrained by unknown mechanisms into combinatorial patterns, which facilitate transitions from uncommitted
A Barski +57 more
core +3 more sources
Dolutegravir induces FOLR1 expression during brain organoid development
Frontiers in Molecular NeuroscienceDuring the first month of pregnancy, the brain and spinal cord are formed through a process called neurulation. However, this process can be altered by low serum levels of folic acid, environmental factors, or genetic predispositions.
Carlo Donato Caiaffa +15 more
doaj +1 more source
Disease Models & Mechanisms, 2018 Human mutations in the planar cell polarity component VANGL2 are associated with the neural tube defect spina bifida. Homozygous Vangl2 mutation in mice prevents initiation of neural tube closure, precluding analysis of its subsequent roles in ...
Gabriel L. Galea +8 more
doaj +1 more source
Large, long range tensile forces drive convergence during [PDF]
, 2018 Indirect evidence suggests that blastopore closure during gastrulation of anamniotes, including amphibians such as Xenopus laevis, depends on circumblastoporal convergence forces generated by the marginal zone (MZ), but direct evidence is lacking.
Davidson, Lance A. +3 more
core +1 more source
EVIDENCE OF COMMUNAL OVIPOSITION AND NEST ABANDONMENT IN THE NORTHERN TWO-LINED SALAMANDER (EURYCEA BISLINEATA, (GREEN, 1818)) IN NORTHEASTERN CONNECTICUT [PDF]
, 2014 Most plethodontid salamanders oviposit their eggs in an individual nest and attend the clutch until hatching. Here, we describe aspects of the reproduction of Eurycea bislineata (Northern Two-lined Salamander) from three field sites in northeastern ...
Ferguson, Taylor F. +2 more
core +2 more sources