Results 51 to 60 of about 12,090 (225)
Neural tube closure: cellular, molecular and biomechanical mechanisms. [PDF]
, 2017 Neural tube closure has been studied for many decades, across a range of vertebrates, as a paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the severe congenital malformations - 'neural tube defects' - that result ...
Copp, AJ +4 more
core +2 more sources
Embryopathological relationship between retained medullary cord and caudal spinal lipoma
Interdisciplinary Neurosurgery, 2022 Purpose: Retained medullary cord (RMC) is a condition in which the cord-like structure (C-LS) is continuous from the conus and extends to the dural cul-de-sac, causing spinal cord tethering, which is thought to originate from the secondary neurulation ...
Takato Morioka +7 more
doaj +1 more source
Exome Sequencing in Prenatally Diagnosed Isolated Neural Tube Defects: A Subtype‐Specific Analysis
Prenatal Diagnosis, EarlyView.ABSTRACT Objective To explore potential genetic contributors across different subtypes of isolated neural tube defects (NTDs) ‐ acrania–exencephaly–anencephaly sequence (AEAS), spinal dysraphism, and encephalocele ‐ using exome sequencing (ES) in a prenatal cohort, with the goal of gaining insight into the molecular diversity underlying these distinct ...
Adi Botvinik +9 more
wiley +1 more source
Hinge point emergence in mammalian spinal neurulation
Proceedings of the National Academy of Sciences, 2022 Significance Spinal neural tube folding shows a transition from medial to dorsolateral neural plate bending sites (hinge points) along the embryo’s body axis. While hinge points are considered an important driving force in neural tube closure, their biomechanical origin is poorly understood.
Veerle de Goederen +3 more
openaire +2 more sources
Teratogenic effects of gabapentin on the skeletal system of Balb/C mice fetuses [PDF]
, 2009 Objectives: To evaluate the effects of gabapentin )GBP( administration on mice fetuses. Methods: This study was carried out in Birjand University of Medical Sciences during 2008.
Afshar, M. +4 more
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Birth Defects Research, Volume 118, Issue 4, April 2026.ABSTRACT Background Animal models remain essential for understanding developmental toxicology, providing insights into how in utero exposures affect fetal and placental outcomes. Litter‐bearing species are widely used due to their efficiency and reproducibility, but conventional approaches often summarize outcomes at the litter level, masking ...
Lauren T. L. Brown +4 more
wiley +1 more source
Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]
, 2019 Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan +4 more
core +2 more sources
Communications Biology, 2022 Various types of progenitors initiate individual organ formation and their crosstalk orchestrates morphogenesis for the entire embryo. Here we show that progenitor exosomal communication across embryonic organs occurs in normal development and is altered
Songying Cao +6 more
doaj +1 more source
Micro Pattern‐Based 3D Cell Culture Platform: An Overview of Technologies and Applications
Exploration, Volume 6, Issue 2, April 2026.Micro patterns are characterized as a coating of specific adhesion matrices on substrates to support cell growth. An overview of micropattern technology to regulate single cell morphology and fates, further focusing on the micro pattern‐based 3D cell culture platform used in the non‐tumor and tumor researches.
Xinglong Zhu +8 more
wiley +1 more source
Investigating the Interactions Between Protocadherin-19 and Ryk and its Effect on Neurogenesis [PDF]
, 2016 Protocadherins are a large, diverse family of neural cell adhesion proteins, but their functions are not understood. Mutations or in several protocadherins have been associated with neurological disorders.
Liebau, Brandon
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