Results 21 to 30 of about 12,090 (225)
A zinc transporter gene required for development of the nervous system. [PDF]
, 2013 The essentiality of zinc for normal brain development is well established. It has been suggested that primary and secondary zinc deficiencies can contribute to the occurrence of numerous human birth defects, including many involving the central nervous ...
Chowanadisai, Winyoo +4 more
core +1 more source
Current perspectives of the signaling pathways directing neural crest induction. [PDF]
, 2012 The neural crest is a migratory population of embryonic cells with a tremendous potential to differentiate and contribute to nearly every organ system in the adult body.
García-Castro, Martín I +1 more
core +2 more sources
Highly efficient manipulation of nervous system gene expression with NEPTUNE
Cell Reports: Methods, 2021 Summary: Genetic loss and gain of function in mice have typically been studied by using knockout or knockin mice that take months to years to generate.
Katrin Mangold +5 more
doaj +1 more source
A gene regulatory network for neural induction
eLife, 2023 During early vertebrate development, signals from a special region of the embryo, the organizer, can redirect the fate of non-neural ectoderm cells to form a complete, patterned nervous system.
Katherine E Trevers +14 more
doaj +1 more source
Prickle1 is required for EMT and migration of zebrafish cranial neural crest [PDF]
, 2019 The neural crest—a key innovation of the vertebrates—gives rise to diverse cell types including melanocytes, neurons and glia of the peripheral nervous system, and chondrocytes of the jaw and skull.
Ahsan, Kamil +4 more
core +1 more source
The Birth of the Eye Vesicle: When Fate Decision Equals Morphogenesis
Frontiers in Neuroscience, 2018 As the embryonic ectoderm is induced to form the neural plate, cells inside this epithelium acquire restricted identities that will dictate their behavior and progressive differentiation.
Florence A. Giger, Corinne Houart
doaj +1 more source
Ptychoderid Hemichordate Neurulation without a Notochord [PDF]
Integrative and Comparative Biology, 2012 Enteropneust hemichordates share several characteristics with chordates, such as a Hox-specified anterior-posterior axis, pharyngeal gill slits, a dorsal central nervous system (CNS), and a juvenile postanal tail. Ptychoderid hemichordates, such as the indirect-developer Ptychodera flava, have feeding larvae and a remarkable capacity to regenerate ...
Shawn, Luttrell +4 more
openaire +2 more sources
Stem Cell Research, 2019 Development of neural tube has been extensively modeled in vitro using human pluripotent stem cells (hPSCs) that are able to form radially organized cellular structures called neural rosettes.
Veronika Fedorova +17 more
doaj +1 more source
Secondary Neurulation Defects-1 : Retained Medullary Cord [PDF]
Journal of Korean Neurosurgical Society, 2020 Retained medullary cord (RMC) is a relatively recent term. Pang et al. newly defined the RMC as a late arrest of secondary neurulation leaving a non-functional vestigial portion at the tip of the conus medullaris. RMC, which belongs to the category of closed spinal dysraphism, is a cord-like structure that is elongated from the conus toward the cul-de ...
Kyung Hyun Kim +2 more
openaire +2 more sources
Dynamic acetylation profile during mammalian neurulation [PDF]
Birth Defects Research, 2019 AbstractBackgroundNeural tube defects (NTDs) result from failure of neural tube closure during embryogenesis. These severe birth defects of the central nervous system include anencephaly and spina bifida, and affect 0.5–2 per 1,000 pregnancies worldwide in humans. It has been demonstrated that acetylation plays a pivotal role during neural tube closure,
Massa, Valentina +11 more
openaire +4 more sources