Results 21 to 30 of about 125,113 (289)
Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse [PDF]
, 2013 Closure of the neural tube during embryogenesis is a crucial step in development of the central nervous system. Failure of this process results in neural tube defects, including spina bifida and anencephaly, which are among the most common birth defects ...
Copp, AJ +4 more
core +1 more source
Neural tube defects: recent advances, unsolved questions, and controversies [PDF]
, 2013 Neural tube defects are severe congenital malformations affecting around one in every 1000 pregnancies. An innovation in clinical management has come from the finding that closure of open spina bifida lesions in utero can diminish neurological ...
Copp, AJ, Greene, NDE, Stanier, P
core +1 more source
Neogenin and RGMa control neural tube closure and neuroepithelial morphology by regulating cell polarity [PDF]
, 2008 In humans, neural tube closure defects occur in 1: 1000 pregnancies. The design of new strategies for the prevention of such common defects would benefit from an improved understanding of the molecular events underlying neurulation. Neural fold elevation
Bradford, DanaKai +5 more
core +1 more source
A case report of triple neural tube defect: revisiting the multisite closure theory
BMC Surgery, 2019 Background Triple neural tube defects are rare. To the author’s knowledge, there are only four reported cases available in the literature up to date. Controversies exist with regards to the development of neural tube defects.
Jayant Kumar Yadav +4 more
doaj +1 more source
Global Pediatric Health, 2020 Neural tube defects remain a major problem in developing countries, but there are limited comprehensive national reports to date in Ethiopia. Therefore, this study aimed to assess the prevalence of neural tube defects and associated factors in Ethiopia ...
Zebenay Workneh Bitew MSc, MPH +3 more
doaj +1 more source
Complex Nature of Neural Tube Defects: A Regional Experience
Gynecology Obstetrics & Reproductive Medicine, 2018 Objective: The underlying gene-environment interaction of fetal neural tube defects is affected by several factors including geography, ethnicity and time. Local features of fetal neural tube defects were described.
Emrah Turhan +3 more
doaj +1 more source
Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]
, 2019 Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan +4 more
core +2 more sources
Emerging Infectious Diseases, 1997 We tested the hypothesis that Cache Valley Virus (CVV), an endemic North American bunyavirus, may be involved in the pathogenesis of human neural tube defects. This investigation followed a 1990 and 1991 south Texas outbreak of neural tube defects with a
J. F. Edwards, K. Hendricks
doaj +1 more source
Neural tube defects: current view on etiology, prenatal prevention, and early diagnosis. A review
Consilium Medicum, 2023 A literature review on the etiology, prevention, and early diagnosis of neural tube defects is presented, focusing on the causes and risk factors for these disorders.
Liliyana A. Chugunova +2 more
doaj +1 more source
Neural tube closure: cellular, molecular and biomechanical mechanisms. [PDF]
, 2017 Neural tube closure has been studied for many decades, across a range of vertebrates, as a paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the severe congenital malformations - 'neural tube defects' - that result ...
Copp, AJ +4 more
core +2 more sources