PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes +6 more
wiley +1 more source
Optical genome mapping identifies rare structural variants in neural tube defects. [PDF]
Sahajpal NS +9 more
europepmc +1 more source
In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley +1 more source
Research advancements in the Use of artificial intelligence for prenatal diagnosis of neural tube defects. [PDF]
Yeganegi M +11 more
europepmc +1 more source
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong +7 more
wiley +1 more source
PCSK9 Loss-of-Function Disrupts Cellular Microfilament Network via LIN28A/HES5/JMY Axis in Neural Tube Defects. [PDF]
Li X +6 more
europepmc +1 more source
Visualizing Specific Tubulin Isotypes and Pathogenic Variants in Cellular Microtubule Arrays
ABSTRACT Eukaryotic cells depend on dynamic microtubule arrays to execute a wide range of functions vital for life. These microtubule filaments are formed through the polymerization of α/β‐tubulin proteins, which can be generated from numerous tubulin genes, or isotypes.
Sareen Fiaz +2 more
wiley +1 more source
The California Alpha-Fetoprotein Screening Program: An Advocacy Program for Handicapped Children [PDF]
Marmion, Pat
core +1 more source
There is a paucity of data regarding the effects of prenatal disease‐modifying therapies (DMTs) for multiple sclerosis (MS), on congenital anomalies in the offspring. Moreover, data on the association with neurodevelopmental disorders are lacking. This is an historical cohort study, within the Israeli Clalit Health Services database (2005–2024) that ...
Bar Rosh +4 more
wiley +1 more source
Exploring Research Trends and Mechanisms: Maternal Diabetes and Neural Tube Defects (1991-2023). [PDF]
Cao L +8 more
europepmc +1 more source

