Letter to the Editor: Further efforts to redce the incidence of neural tube defects [PDF]
Brent, Robert L
core +1 more source
Abstract Background Midline establishment is a fundamental process during early embryogenesis for Bilaterians. Midline morphogenesis in non‐amniotes can occur without mitosis, through Planar Cell Polarity (PCP) signaling. By contrast, amniotes utilize both cellular processes for developing the early midline landmark, the primitive streak (PS).
Zhiling Zhao, Rieko Asai, Takashi Mikawa
wiley +1 more source
Fetoscopic two-layer closure for open neural tube defects: prospective study of obstetric, surgical and perinatal outcomes in the first 50 cases. [PDF]
Giné C +9 more
europepmc +1 more source
Abstract Background Gene transcription is crucial for embryo and postnatal development and is regulated by the Mediator complex. Mediator is comprised of four submodules, including the kinase submodule (CKM). The CKM consists of MED13, MED12, CDK8, and CCNC.
Anna K. Leinheiser +5 more
wiley +1 more source
<i>NUAK2</i> Pathogenic Variants Are Definitively Associated with Neural Tube Defects in Humans: New Genotype-Phenotype Correlation and Review of the Literature. [PDF]
Mastromoro G +9 more
europepmc +1 more source
The role of Rho GTPases in facial morphogenesis
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley +1 more source
Trends in neural tube defects in Scotland in 2000-2021 prior to the introduction of mandatory folic acid fortification of non-wholemeal wheat flour: a population-based study. [PDF]
Kirolos A +4 more
europepmc +1 more source
Abstract Background Endocytosis constitutes a fundamental cellular process governing development through coordinated regulation of plasma membrane remodeling and ciliogenesis, processes essential for cell shape changes and tissue development. Although Twist1 null embryos display complete cranial neural tube (NT) closure defects and conditional knockout
Derrick Thomas +8 more
wiley +1 more source
Prevalence of Babies Born With Neural Tube Defects and Geospatial Mapping of Therapeutic Services: A Systematic Review. [PDF]
Zolo Y, David DU, Isiagi M, Maswime S.
europepmc +1 more source

