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International Journal of Neurologic Physical Therapy, 2021 Summary/Abstract Background: Neural tube defects (NTDs) are one of the commonest malformations with worldwide prevalence of 1-3 per1000 live births. They are resulted by failure of neural tube to close during neurulation in 21-28 embryonic days and it’s a multi-factorial in etiology.
Poster Mutambo, Paul Siapiila
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Embryology Applied to Neural Tube Defects (NTDs)
2008Spina bifida is a frequent congenital malformation involving the spinal cord. It was first described by Nicolas Tulp in 1651 (Figs. 2.1 and 2.2). Nicolas Tulp is also famous for the portrait Rembrandt painted of him during his anatomical lessons. The term spina bifida was suggested by Tulp and proposed solely to describe the vertebral anomaly that was ...
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A cohort study of neural tube defects (NTD) in Denmark covering the first seven years of life
Child's Nervous System, 1987In the County of Fyn, Denmark, which is a well-delimited region comprising a 10% representative sample of the total population, ten complete one year cohorts of newborn were scrutinized for neural tube defects (NTD). Among 66,000 births, 71 cases with NTD were observed.
J, Haase +4 more
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Genetic studies in neural tube defects. NTD Collaborative Group.
Pediatric neurosurgery, 2000Neural tube defects (NTD) are one of the most common birth defects and are caused by both environmental and genetic factors. The approach to identifying the genes predisposing to NTD, through linkage analysis and candidate gene analysis, is reviewed along with characteristics of a large, nationally ascertained cohort of families.
E C, Melvin +23 more
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Maternal Caffeine Intake, Selected Metabolic Gene Variants, and Neural Tube Defects (NTDs)
Annals of Epidemiology, 2007Purpose Using data from the National Birth Defects Prevention Study, we examined associations between NTDs and maternal caffeine intake, gene variants for caffeine metabolism, and their joint effects. Methods Total average caffeine per day was summed from maternal interview reports of coffee, tea, soda, and chocolate intake.
R.J. Schmidt +5 more
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Journal of Applied Genetics, 2006
The birth incidence of neural tube defect (NTD) cases in British Columbia (B.C.), and elsewhere in North America, is reported to be declining. This decline is being attributed to folic acid (FA) supplementation and food fortification, but 2nd trimester prenatal screening of pregnancies for NTDs and other congenital anomalies has increased during this ...
Margot I, Van Allen +12 more
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The birth incidence of neural tube defect (NTD) cases in British Columbia (B.C.), and elsewhere in North America, is reported to be declining. This decline is being attributed to folic acid (FA) supplementation and food fortification, but 2nd trimester prenatal screening of pregnancies for NTDs and other congenital anomalies has increased during this ...
Margot I, Van Allen +12 more
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Reproductive Toxicology, 1995
Both the antiepileptic drug valproic acid (VPA) and ethanol interfere with fetal folate metabolism, which may contribute to their mechanism of teratogenesis. Therefore, the possible interaction between VPA and ethanol was investigated in mice. Ethanol (2 x 2.5 g/kg) was given orally 4 and 1 h prior to VPA (300 and 400 mg/kg, SC) in day 8.25 pregnant ...
Elmazar, Mohamed M., Nau, Heinz
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Both the antiepileptic drug valproic acid (VPA) and ethanol interfere with fetal folate metabolism, which may contribute to their mechanism of teratogenesis. Therefore, the possible interaction between VPA and ethanol was investigated in mice. Ethanol (2 x 2.5 g/kg) was given orally 4 and 1 h prior to VPA (300 and 400 mg/kg, SC) in day 8.25 pregnant ...
Elmazar, Mohamed M., Nau, Heinz
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Management of infants with neural tube defects (NTDs) in NICU
2017Neural tube defects (NTDs) are a group of congenital malformations of the central nervous system, which derive from an altered embryological development during neurulation. The different types of NTDs are closely related to their onset in the embryonic period; precocity is an index of greater severity of clinical manifestation.
Passalacqua M. I. +7 more
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Genetic Susceptibility to Neural Tube Defect (NTD) and Hyperhomocysteinemia
2022Govind Prasad Dubey +4 more
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