Results 91 to 100 of about 54,178 (260)

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Trigeminal neuralgia, migraine and sympathetic hyperactivity in a patient with Parry–Romberg syndrome

, 2006
Parry–Romberg syndrome is a rare disorder of unknown aetiology that involves slowly progressive but self-limited wasting of subcutaneous tissues on one side of the face, usually in the distribution of a branch of the trigeminal nerve.
Drummond, P.D., Finch, P.M., Hassard, S.
core   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Occipital Neuralgia

, 2018
According to the International Headache Society, occipital neuralgia is classified as a cranial neuralgia. It is characterized by paroxysmal pain in the distribution of the greater, lesser, or third occipital nerve.
Andrea Dellaria, Nirav N. Shah, Helene Rubeiz   +2 more
core   +1 more source

Bloqueo caudal epidural para el tratamiento del síndrome de atrapamiento del nervio pudendo

Revista Cubana de Anestesiología y Reanimación, 2015
Introducción: el síndrome de atrapamiento del nervio pudendo es generalmente desconocido y suele ser mal diagnosticado o confundido con otras enfermedades. Lo describió por primera vez Amarenco en 1987.
Mario Luis Pérez Rodríguez, Ariadna García Rodríguez   +1 more
doaj  

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Neuropathic pain in cerebral palsy and related genetic conditions: A scoping review of prevalence, characteristics, and management

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To map existing evidence on neuropathic pain in cerebral palsy (CP) and related genetic conditions, including prevalence, descriptors, assessment methods, and management. Method Following prospective registration, five databases (Ovid MEDLINE, Embase, CINAHL, Web of Science, Google Scholar) were searched in June 2025.
Aayushi Khillan, Sanya Verma, Hannah Yeomans, Karen Bau, Caitlin Doyle, Monica S. Cooper, David J. Amor, Carolyn Berryman, Adrienne Harvey   +8 more
wiley   +1 more source

Electrical stimulation decreases neuralgic pain after trigeminal deafferentation

, 2008
Trigeminal nerve activity mediates head pain after cranial injuries, and also contributes to idiopathic syndromes such as cluster headache and trigeminal neuralgia. Nevertheless, chronic facial pain sometimes develops after lesion of the trigeminal nerve.
Treleaven-Hassard, S., Drummond, P.D.
core   +1 more source

Evolving treatments for Sjögren disease: current approaches and emerging targets

Internal Medicine Journal, EarlyView.
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani, Adrian Y. S. Lee, Maureen Rischmueller, Alberta Hoi   +3 more
wiley   +1 more source

Essential medications in palliative care: an updated survey of Australian and New Zealand medical practitioners practising palliative care

Internal Medicine Journal, EarlyView.
Abstract Background Palliative care patients experience complex symptoms requiring varied pharmacological management. Medication choice depends on the underlying aetiology of symptoms, guideline recommendations, clinician preference and medication availability.
Jack Power, Tim Luckett, Richard McNeill, David Currow, Amanda Landers, Gregory B. Crawford, Slavica Kochovska, Philip Good, Jessica Boyley, Sungwon Chang, Lisa Mounsey   +10 more
wiley   +1 more source