Results 81 to 90 of about 59,055 (217)
MedicinaBackground and Objectives: Neuropathic pain presents a significant therapeutic challenge, often due to resistance to opioids. This study examined how selective adenosine receptor agonists and allopurinol modulate spinal mu-opioid receptor (MOR) mRNA ...
Jaesuk Kim +3 more
doaj +1 more source
PM&R, EarlyView.Abstract Background Altered interoception, the sense of signals from inside the body, is linked to chronic pain. No studies to date have examined whether interoceptive sensibility, one's self‐reported beliefs about the body and tendencies to be internally focused, changes following participation in an interdisciplinary pain management program (IPMP ...
Stephanie Voss +4 more
wiley +1 more source
Phytotherapy Research, EarlyView.Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko +3 more
wiley +1 more source
Australian Dental Journal, EarlyView.Population: Adults with non‐odontogenic orofacial pain, including temporomandibular disorders (TMDs), burning mouth syndrome (BMS), post‐traumatic trigeminal neuropathy (PTTN), and other chronic non‐odontogenic orofacial pain referral cohorts. Exposure: Sleep disturbances assessed using the Pittsburgh Sleep Quality Index (PSQI), Basic Nordic Sleep ...
Jainy Shah +3 more
wiley +1 more source
, 2016 Neuralgia trójdzielna należy do najcięższych bólów w obrębie twarzy. Choć została opisana przez wielu badaczy, dzisiaj nazywa się ją chorobą Fothergilla, co upamiętnia przedstawienie neuralgii trójdzielnej przez tego uczonego w 1773 roku ...
Jan Kochanowski
core +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Bloqueo caudal epidural para el tratamiento del síndrome de atrapamiento del nervio pudendo
Revista Cubana de Anestesiología y Reanimación, 2015 Introducción: el síndrome de atrapamiento del nervio pudendo es generalmente desconocido y suele ser mal diagnosticado o confundido con otras enfermedades. Lo describió por primera vez Amarenco en 1987.
Mario Luis Pérez Rodríguez +1 more
doaj
Peripheral targets for neuropathic pain
British Journal of Pharmacology, EarlyView.Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour +3 more
wiley +1 more source
, 2018 According to the International Headache Society, occipital neuralgia is classified as a cranial neuralgia. It is characterized by paroxysmal pain in the distribution of the greater, lesser, or third occipital nerve.
Andrea Dellaria +2 more
core +1 more source