Results 111 to 120 of about 113,525 (312)

T cells from newly diagnosed multiple sclerosis patients have enhanced responsiveness to CD46 activation

open access: yesClinical and Experimental Neuroimmunology, EarlyView.
Abstract Objective To evaluate the responsiveness of T cells from newly diagnosed multiple sclerosis (MS) patients to CD46 co‐stimulation, a membrane co‐factor protein potentially involved in MS pathogenesis. Methods T cells from MS patients and non‐diseased symptomatic controls (SC) were activated in vitro with or without αCD46 antibody co‐stimulation.
Linda Sundvall   +6 more
wiley   +1 more source

Structure of myelin P2 protein from equine spinal cord [PDF]

open access: yes, 2005
Equine P2 protein has been isolated from horse spinal cord and its structure determined to 2.1 Å. Since equine myelin is a viable alternative to bovine tissue for large-scale preparations, characterization of the proteins from equine spinal cord ...
Freer, A.A.   +5 more
core   +1 more source

Effect of time to initiation and dose of methylprednisolone on outcome in multiple sclerosis‐related optic neuritis

open access: yesClinical and Experimental Neuroimmunology, EarlyView.
Abstract Objectives It is known that the benefit of intravenous methylprednisolone (IVMP) in multiple sclerosis‐related optic neuritis (MS‐ON) is limited to an accelerated recovery. We aimed to evaluate the impact of time from symptoms onset to IVMP initiation and of IVMP dose on visual recovery among people with MS‐ON.
Hadar Gilad   +3 more
wiley   +1 more source

Correlation of Structure With Function: Future Utilities for Optical Coherence Tomography Angiography in Neuro‐Ophthalmology

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Optical coherence tomography angiography is a burgeoning imaging modality in Ophthalmology. In this review, we outline the breadth of potential utility for optical coherence tomography angiography for diagnosis and prognostication in neuro‐ophthalmology.
Marzieh Tahmasebi Sarvestani   +2 more
wiley   +1 more source

Optic neuritis updates (ORP-57) [PDF]

open access: yesNeurology Letters, 2023
The optic nerve is a relatively small structure, with a total length of 50 mm, but there are numerous causes of optic nerve disorders, including: inflammation, tumours, vascular disorders, metabolic diseases, infections, drugs, systemic diseases, genetic
Nahid Beladi Moghadam
doaj  

Imaging of adult ocular and orbital pathology - a pictorial review [PDF]

open access: yes, 2014
Orbital pathology often presents a diagnostic challenge to the reporting radiologist. The aetiology is protean, and clinical input is therefore often necessary to narrow the differential diagnosis.
Brennan, Paul   +8 more
core   +1 more source

Targeting Oxidative Stress for Treatment of Glaucoma and Optic Neuritis

open access: yesOxidative Medicine and Cellular Longevity, 2017
Glaucoma is a neurodegenerative disease of the eye and it is one of the leading causes of blindness. Glaucoma is characterized by progressive degeneration of retinal ganglion cells (RGCs) and their axons, namely, the optic nerve, usually associated with ...
A. Kimura   +5 more
semanticscholar   +1 more source

Diagnostic Ability of Transverse Axial Images Obtained by Optical Coherence Tomography for Detecting Anterior Displacement of Peripapillary Tissues in Papilledema

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the diagnostic ability of optical coherence tomography (OCT) images to detect posterior pole deformation and anterior displacement of the optic disc (ADOD) in papilledema before and after intracranial pressure reduction with medical treatment.
Gabriel Castilho S. Barbosa   +5 more
wiley   +1 more source

Tapering Oral Steroid Treatment After IV Methylprednisolone Pulse Therapy in Demyelinating Optic Neuritis

open access: yesCaspian Journal of Neurological Sciences, 2018
Background: Optic neuritis is an inflammation of the optic nerve. Because of importance of vision for human, management of optic neuritis is an important issue in neurology.
Seyed-Ehsan Mohammadianinejad   +6 more
doaj  

Late-onset ulnar neuritis following treatment of lepromatous leprosy infection.

open access: yesPLoS Neglected Tropical Diseases, 2019
Neuritis is a frequent complication of Myocobacteria leprae infection and treatment due to the variety of mechanisms through which it can occur. Not only can mycobacterial invasion into peripheral nerves directly cause damage and inflammation, but immune-
Trevor Wellington, Christina Schofield
doaj   +1 more source

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