Results 21 to 30 of about 362 (162)

NeuroAid II (MLC901) and polypharmacy in stroke and the risk of hepatotoxicity: a case report

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background NeuroAid II (MLC901) is a promising therapy for stroke patients who present outside of therapeutic window for reperfusion therapy. Studies have proven its efficacy in ischemic stroke; however, data of drug safety and combination with other ...
Anna Misya’il Abdul Rashid, Mohamad Syafeeq Faeez Md Noh, Abdul Hanif Khan Yusof Khan, Wei Chao Loh, Janudin Baharin, Azliza Ibrahim, Liyana Najwa Inche Mat, Wan Aliaa Wan Sulaiman, Fan Kee Hoo, Fazah Akhtar Hanapiah, Hamidon Basri   +10 more
doaj   +1 more source

Molecular Mechanism of MLC 901 in Acute Ischemic Stroke: A Review. [PDF]

Stroke Res Treat
Ischemic stroke is the leading cause of stroke all around the world. Ischemic stroke can cause severe and irreversible damage to the brain. Brain neuroprotection is a promising treatment strategy. Moleac (MLC) 901, a traditional Chinese medicine, is one alternative adjunctive therapy that enhances neuroprotection.
Hunaifi I, Bintang AK, Tammasse J, Wahid I, Hatta M, Islam AA, Zainuddin AA, Sugianto P.   +7 more
europepmc   +2 more sources

Traditional Chinese medicines in the management of cardiovascular diseases:A comprehensive systematic review [PDF]

, 2016
AIMS: The aim was to perform a systematic review of the efficacy of traditional Chinese medicines (TCM) in cardiovascular disease. METHODS: Electronic databases were searched up to 11 November 2015 for all randomized‐controlled trials evaluating the ...
Ferro, Albert, Layne, Kerry
core   +4 more sources

Neuro‐HIV—New insights into pathogenesis and emerging therapeutic targets

The FASEB Journal, Volume 37, Issue 12, December 2023., 2023
HIV infection (blue circle) by definition is the key contributor to the pathogenesis of HAND with many other contributing factors greatly influencing the progression of the disease. These factors are grouped according to their common features; HAND is at the intersection of these groups (dash‐line circle).
Dmitri Sviridov, Michael Bukrinsky
wiley   +1 more source

Glioblastoma following Hemorrhagic Stroke: A Case Report [PDF]

, 2021
Objective: To report a glioblastoma (GBM) case preceded by a hemorrhagic stroke.Methods: This case reported a 53-year-old male presenting at at Murni Teguh Memorial Hospital, Medan, Indonesia, with a chief complaint of an altered mental state.
Dewanto, Bayu, Kevin, Kevin, Yamamoto, Zulham   +2 more
core   +4 more sources

NeuroAIDS in Africa [PDF]

Journal of Neurovirology, 2010
In July 2009, the Center for Mental Health Research on AIDS at the National Institute of Mental Health organized and supported the meeting “NeuroAIDS in Africa.” This meeting was held in Cape Town, South Africa, and was affiliated with the 5th IAS Conference on HIV Pathogenesis, Treatment and Prevention.
Robertson, Kevin, Liner, Jeff, Hakim, James, Sankalé, Jean-Louis, Grant, Igor, Letendre, Scott, Clifford, David, Gallo Diop, Amadou, Jaye, Assan, Kanmogne, Georgette, Njamnshi, Alfred, Langford, T. Dianne, Weyessa, Tufa Gemechu, Wood, Charles, Banda, Mwanza, Hosseinipour, Mina, Sacktor, Ned, Nakasuja, Noeline, Bangirana, Paul, Paul, Robert, Joska, John, Wong, Joseph, Boivin, Michael, Holding, Penny, Kammerer, Betsy, Van Rie, Annelies, Ive, Prudence, Nath, Avindra, Lawler, Kathy, Adebamowo, Clement, Royal, Walter, III, Joseph, Jeymohan   +31 more
openaire   +2 more sources

Regional Analysis of Intact and Defective HIV Proviruses in the Brain of Viremic and Virally Suppressed People with HIV

Annals of Neurology, Volume 94, Issue 4, Page 798-802, October 2023., 2023
Here, we provide the first regional analysis of intact and defective HIV reservoirs within the brain. Brain tissue from both viremic and virally suppressed people with HIV (PWH) harbored HIV pol DNA in all regions tested, with lower levels present in basal ganglia and cerebellum relative to frontal white matter.
Thomas A. Angelovich, Catherine R. Cochrane, Jingling Zhou, Carolin Tumpach, Sarah J. Byrnes, Janna Jamal Eddine, Emily Waring, Kathleen Busman‐Sahay, Claire Deleage, Trisha A. Jenkins, Anna C. Hearps, Stuart Turville, Paul R. Gorry, Sharon R. Lewin, Bruce J. Brew, Jacob D. Estes, Michael Roche, Melissa J. Churchill   +17 more
wiley   +1 more source

HIV/neuroAIDS biomarkers [PDF]

Progress in Neurobiology, 2017
HIV infection often causes neurological symptoms including cognitive and motor dysfunction, which have been collectively termed HIV/neuroAIDS. Neuropsychological assessment and clinical symptoms have been the primary diagnostic criteria for HIV/neuroAIDS, even for the mild cognitive and motor disorder, the most prevalent form of HIV/neuroAIDS in the ...
Pejman, Rahimian, Johnny J, He
openaire   +2 more sources

Retroviral b‐Zip protein (HBZ) contributes to the release of soluble and exosomal immune checkpoint molecules in the context of neuroinflammation

Journal of Extracellular Biology, Volume 2, Issue 7, July 2023., 2023
Abstract HTLV‐I‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic, progressive, neuroinflammatory demyelinating condition of the spinal cord. We have previously shown that aberrant expression and activity of immune checkpoint (ICP) molecules such as PD‐1 and PD‐L1/PD‐L2, negatively associates with the cytolytic potential of T ...
Julie Joseph, Thomas A. Premeaux, Daniel O. Pinto, Abhishek Rao, Shrobona Guha, Amanda R. Panfil, Alison J. Carey, Lishomwa C. Ndhlovu, Elke S. Bergmann‐Leitner, Pooja Jain   +9 more
wiley   +1 more source

Editorial NeuroAIDS review [PDF]

AIDS, 2011
NeuroAIDS is a disease that incorporates both infectious and degenerative pathophysiologic pathways. It has a known cause, has several animal models, and is under investigation and treatment using multiple avenues, in vivo and in vitro [1–7]. Select highlights from the spectrum of NeuroAIDS research predominantly related to human immunodeficiency virus-
Paul, Shapshak, Pandjassarame, Kangueane, Robert K, Fujimura, Deborah, Commins, Francesco, Chiappelli, Elyse, Singer, Andrew J, Levine, Alireza, Minagar, Francis J, Novembre, Charurut, Somboonwit, Avindra, Nath, John T, Sinnott   +11 more
openaire   +2 more sources