Results 101 to 110 of about 268,541 (353)

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

The structure basic of neurobiology

, 1983
xii+417hlm ...
JANES, EDWARD G.
core  

Teaching Neurobiology in Psychiatry

, 2018
The relationship between psychiatry and neuroscience has been constantly evolving since the conception of our field. The past two decades have witnessed a steep rise in research related to neurobiology in psychiatry.
Samir A. Sabbag, Nemeroff, Charles B., Saveanu, Radu V., Alhajji, Lujain, Stahl, Stephen M., Stephen M. Stahl, Sabbag, Samir A., Lujain Alhajji, Radu V. Saveanu, Charles B. Nemeroff   +9 more
core   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Neurobiology of Stroke

, 1998
Publisher Summary This chapter summarizes the clinical features of stroke and discusses the status of the stroke therapy. Pathophysiological mechanisms underlying ischemic damage are discussed in terms of animal experimentation and treatment regimens. In view of the high morbity and mortality associated with stroke and cerebrovascular disease, animal
openaire   +2 more sources

Downward causation and neurobiology of free will

, 2009
Berlin Heidelberg291 p.: bibl.
Murphy, Nancey, edit., O'Connor, Timothy, edit., Ellis, George F.R., edit.   +2 more
core  

The neurobiology of human crying [PDF]

, 2019
The production of emotional tears appears to be uniquely present in Homo sapiens. Despite the ubiquity of this human behavior, research is only just beginning to uncover the neurobiologic underpinnings of human emotional crying.
Gracanin, A., Vingerhoets, A.J.J.M., Bylsma, L.M.   +2 more
core   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Integrating weighted gene co-expression network analysis and machine learning to elucidate neural characteristics in a mouse model of depression

Frontiers in Psychiatry
IntroductionAn AI-assisted deep learning strategy was applied to analyze the neurobiological characteristics of depression in mouse models. Integration of weighted gene co-expression network analysis (WGCNA) with the random forest algorithm enabled the ...
Jinli Gao, Qinglang Wang, Jie Liu, Siqian Zheng, Jiahong Liu, Zhiyong Gao, Cheng Zhu   +6 more
doaj   +1 more source