Results 261 to 270 of about 268,541 (353)

Dopaminergic novelty detection and theta oscillations: Virtual reality‐based adaptive interventions for cognitive enhancement in aging

Ibrain, EarlyView.
Aging‐related cognitive decline is associated with reduced dopaminergic signaling and disrupted theta oscillations, which together impair novelty detection and memory formation. This review shows how VR environments can be used to deliver adaptive, novelty‐rich stimuli that engage dopaminergic circuits and entrain theta rhythms, thereby enhancing ...
Abraham Olufemi Asuku, Ayodeji Johnson Ajibare   +1 more
wiley   +1 more source

Roles of histone lysine methylation in neurodevelopment and related disorders

Ibrain, EarlyView.
This graphical abstract centers on the theme of dynamic balance and systematically outlines the role of histone lysine methylation in neurodevelopment and related disorders. The figure first presents two key classes of regulators that control this balance—“writers” and “erasers”—and then indicates how interactions among different epigenetic ...
Yun Chen, Yi Zhang, Hong Zhang, Xiaoli Liang   +3 more
wiley   +1 more source

Safety and short-term outcomes of lecanemab for Alzheimer's disease in China: a multicentre study. [PDF]

Brain
Li LL, Wang RZ, Wang Z, Hu H, Xu W, Zhu L, Sun Y, Chen KL, Chen SF, He XY, Yuan MY, Huang YY, Liu XY, Liu P, Ye QY, Wang J, Ju ZZ, Zhang W, Hu B, Guo Y, Cao XY, Li YX, Zuo CT, Cheng W, Jiang T, Tan L, Chen XC, Zhao QH, Cui M, Peng GP, Xin JW, Yu JT.   +31 more
europepmc   +1 more source

The impact of exercise on cognitive function and brain health across the lifespan: A systematic review

Ibrain, EarlyView.
This systematic review of 37 studies demonstrates that aerobic, resistance, and combined exercise enhance cognitive function and brain health across all ages. Exercise promotes neuroplasticity, upregulates brain‐derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF), and mitigates age‐related cognitive decline, establishing ...
Issam AbuQeis, Abeer Teeti, Amro Titi
wiley   +1 more source

Gene deletion of Klotho in the dentate gyrus does not affect the number of adult-born granule cells. [PDF]

Sci Rep
Kraus P, Marunde M, Ryzynski A, Düzel E, Kaether C, Kreutz MR, Oelschlegel AM.   +6 more
europepmc   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Correction to "Neuropathological Characterisation of McLeod Syndrome With a Proposed New Grading System". [PDF]

Neuropathol Appl Neurobiol
europepmc   +1 more source

Multimorbidity patterns and hospitalizations due to lower respiratory tract infections: a 15-year population-based cohort study. [PDF]

Age Ageing
Franza L, Gentili S, Gregorio C, Beridze G, Marengoni A, Maggi S, Calderón-Larrañaga A, Vetrano DL.   +7 more
europepmc   +1 more source