Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma.
BACKGROUND Preclinical and preliminary clinical data indicate that ch14.18, a monoclonal antibody against the tumor-associated disialoganglioside GD2, has activity against neuroblastoma and that such activity is enhanced when ch14.18 is combined with ...
A. Yu+19 more
semanticscholar +1 more source
Graphene oxide nanoribbons induce autophagic vacuoles in neuroblastoma cell lines [PDF]
Since graphene nanoparticles are attracting increasing interest in relation to medical applications, it is important to understand their potential effects on humans. In the present study, we prepared graphene oxide (GO) nanoribbons by oxidative unzipping
Fico, Flavia+7 more
core +2 more sources
Primary orbital neuroblastoma with intraocular extension
Neuroblastoma is an undifferentiated malignancy of primitive neuroblasts. Neuroblastoma is among the most common solid tumors of childhood. Orbital neuroblastoma is typically a metastatic tumor.
Muthukrishnan Vallinayagam+4 more
doaj +1 more source
Emerging Neuroblastoma 3D In Vitro Models for Pre-Clinical Assessments
The potential of tumor three-dimensional (3D) in vitro models for the validation of existing or novel anti-cancer therapies has been largely recognized.
Diana Corallo+8 more
doaj +1 more source
Growth of a rat neuroblastoma cell line in serum-free supplemented medium.
The rat neuroblastoma B104 cell line, which originated in the central nervous system, was able to proliferate in the absence of serum in synthetic medium supplemented with insulin, transferrin, progesterone, selenium, and putrescine.
J. Bottenstein, G. Sato
semanticscholar +1 more source
Targeted radiotherapy of neuroblastoma: future directions [PDF]
No abstract ...
Gaze, Mark N.+4 more
core +2 more sources
A Quantitative Analysis of Localized Robustness of MYCN in Neuroblastoma [PDF]
The amplification of the gene MYCN (V-myc myelocytomatosis viral-valeted oncogene, neuroblastoma derived) has been a well-documented indicator for poor prognosis in neuroblastoma, a childhood cancer. Unfortunately, there has been limited success in understanding MYCN functionality in the landscape of neuroblastoma and more importantly, given that MYCN ...
arxiv
The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children : a review [PDF]
Cell-free DNA profiling using patient blood is emerging as a non-invasive complementary technique for cancer genomic characterization. Since these liquid biopsies will soon be integrated into clinical trial protocols for pediatric cancer treatment ...
Astrahantseff, Kathy+12 more
core +2 more sources
A multiobjective deep learning approach for predictive classification in Neuroblastoma [PDF]
Neuroblastoma is a strongly heterogeneous cancer with very diverse clinical courses that may vary from spontaneous regression to fatal progression; an accurate patient's risk estimation at diagnosis is essential to design appropriate tumor treatment strategies.
arxiv
A Segmentation Method for fluorescence images without a machine learning approach [PDF]
Background: Image analysis applications in digital pathology include various methods for segmenting regions of interest. Their identification is one of the most complex steps, and therefore of great interest for the study of robust methods that do not necessarily rely on a machine learning (ML) approach.
arxiv