Results 261 to 270 of about 283,064 (357)

Role of human RNase 7 in neuronal and glial cell models: moving towards an unexpected new functional link

The FEBS Journal, EarlyView.
Human RNase 7 is known to exert antimicrobial activity in epithelial tissues. Here, using SH‐SY5Y and U‐87 MG, neuroblastoma and glioblastoma cell lines, respectively, we found that RNase 7 enhances immune responses to LPS stimulation by reducing the expression of pro‐inflammatory cytokines, nitric oxide, and ROS.
Rosanna Culurciello, Maria Cristiano, Ilaria Di Nardo, Ida Palumbo, Erika Piccolo, Rosario Oliva, Andrea Bosso, Aldo Donizetti, Eugenio Notomista, Elio Pizzo   +9 more
wiley   +1 more source

Neuroblastoma in Childhood: Biological Insights, Risk Stratification, and Advances in Multimodal Therapy. [PDF]

J Clin Med
De Bona A, Barbieri M, Rinaldi N, Esposito S.   +3 more
europepmc   +1 more source

Effects of imeglimin on experimental diabetic neuropathy in streptozotocin‐induced diabetic rats

Journal of Diabetes Investigation, EarlyView.
Imeglimin exerted neuroprotective effects in a type 1 diabetic neuropathy model, improving sensory nerve conduction, sciatic nerve blood flow, and intraepidermal nerve fiber density. In vitro, imeglimin promoted neurite outgrowth in a DRG‐derived hybridoma cell line, supporting a direct neurotrophic action.
Wataru Nihei, Ayako Kato, Takuma Sato, Masahiro Yamaguchi, Tatsuhito Himeno, Nobuhisa Nakamura, Kazunori Sango, Keiko Naruse, Jiro Nakamura, Hideki Kamiya, Koichi Kato   +10 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

CCL2: A double-edged sword in neuroblastoma, with a critical role in MYCN-amplified tumors. [PDF]

Transl Oncol
Jannot L, Gazeu A, Bendriss-Vermare N, Pochon C, Sartelet H.   +4 more
europepmc   +1 more source

Delivery of miR-25802 via Small Vesicles Protects Against Mitochondrial Injury, Oxidative Stress, and Neuroinflammation in Alzheimer's Disease. [PDF]

Mol Neurobiol
Çelik H, Dalkılınç E, Aydın Ş, Çelik O, Küçükler S, Topal A, Akay R, Gönüllü S, Yıldız MO, Alım B, Özdemir S.   +10 more
europepmc   +1 more source

A constitutional translocation T(1;17)(P36.2;Q11.2) in a neuroblastoma patient disrupts NBPF1, a novel putative tumor suppressor gene [PDF]

, 2008
Andries, Vanessa, Staes, Katrien, Van Roy, Frans, Vandepoele, Karl   +3 more
core   +1 more source

A Case of Pediatric Spitz Melanoma With a ZEB2::ALK Fusion

Pediatric Dermatology, EarlyView.
ABSTRACT We present a rare case of Spitz melanoma in a 3‐year‐old male patient with a ZEB2::ALK fusion. This ALK‐fused tumor exhibited aggressive behavior, recurring after an initial wide local excision and progressing despite neoadjuvant immunotherapy with a PD‐1 inhibitor.
Nathanael C. Jensen, Shadai Gociman, Sarah D. Cipriano, Casey Mehrhoff   +3 more
wiley   +1 more source

Ribosomal modifications are associated with mesenchymal fate selection in the neural crest lineage. [PDF]

Nat Commun
Poverennaya I, Murtazina A, Li L, Maili L, Sourada L, Montano-Gutierrez LF, Galimullina R, Steinschaden T, Kaiser M, Zikmund T, Goralija A, Gao T, Attina A, Clara O, Bartenhagen C, Erickson A, Gershtein Y, Chen S, Polaskova K, Sterba J, Semasch B, Anderson ER, Prakash V, Vincent T, Arceo M, Kogner P, Schlisio S, Kharchenko PV, David A, Kaiser J, Fischer M, Skoda J, Trainor PA, Chagin AS, Adameyko I.   +34 more
europepmc   +1 more source

Zebrafish as a practical and convenient model for the study of photodynamic and photothermal therapy of solid tumors: A scoping review

Photochemistry and Photobiology, EarlyView.
Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson, Alexander Fiorentino, Brian W. Booth, Valery Bliznyuk, Diana Ivankovic, Luigi Boccuto   +5 more
wiley   +1 more source