Results 61 to 70 of about 28,585 (159)

From transporter to motor: Evolutionary and structural insights into the emergence of prestin's area‐motor activity in mammals

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Prestin, a member of the SLC26A family, is essential for the electromotility of mammalian outer hair cells, converting voltage changes into mechanical work. In contrast, nonmammalian orthologues function as anion transporters. To investigate the molecular and structural basis of this functional divergence, we performed ancestral sequence ...
Nicolás Fuentes‐Ugarte   +6 more
wiley   +1 more source

Fraturas do sistema penal: o sintoma das falsas memórias na prova testemunhal [PDF]

open access: yes, 2013
This thesis aims to evaluate the effects of false memories in relation to witnesses in the processes of criminalization and, in addition, provide preventive alternatives. Therefore, identifying ways of addressing the issue not only in the Brazilian legal
Ávila, Gustavo Noronha de
core  

Blood‐Based Epigenetic Signatures in Brazilian Males With Alcohol Use Disorder

open access: yesAddiction Biology, Volume 31, Issue 5, May 2026.
This study represents the first epigenome‐wide association analysis of Alcohol Use Disorder (AUD) in a genetically and culturally diverse Brazilian cohort. Genome‐wide DNA methylation profiling revealed hypomethylation in genes and pathways related to neuronal development, synaptic organization, intracellular signaling and cellular stress responses in ...
Laís da Silva Pereira‐Rufino   +15 more
wiley   +1 more source

Possible Fortgetfulness : the hermeneutic memory of Paul Ricoeur [PDF]

open access: yes, 2009
O presente trabalho analisa as considerações do filósofo francês Paul Ricoeur sobre o Esquecimento, as quais são resultantes de uma hermenêutica da memória e de uma epistemologia da história.
Oliveira, Emerson Dionisio Gomes de
core  

Neurociências e psicanálise

open access: yesEstilos da Clínica, 2018
A partir de um entendimento integrativo entre psicanálise e neurociências, busca-se compreender a etiologia do autismo. Trata-se de uma revisão bibliográfica narrativa que abarcou dados da história e do conceito de autismo por meio de uma pesquisa ...
Marina da Rosa Vilani   +1 more
doaj   +1 more source

Endocannabinoid system gene expression in mesocorticolimbic brain regions of individuals with alcohol use disorder: A descriptive study

open access: yesAddiction, Volume 121, Issue 5, Page 1179-1189, May 2026.
Abstract Aims To describe differences in the expression of genes encoding cannabinoid receptors (CNR1, CNR2), the associated receptor GRP55 and the enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGLL) between individuals with alcohol use disorder (AUD) and controls in key mesocorticolimbic brain regions.
María Salud García‐Gutiérrez   +5 more
wiley   +1 more source

Assistência Fisioterapêutica no Programa Interdisciplinar de Atenção a Hemiplégicos Pós-Acidente Vascular Cerebral: Uma Abordagem de Terapia em Grupo. [PDF]

open access: yes, 2014
Trabalho apresentado no 31º SEURS - Seminário de Extensão Universitária da Região Sul, realizado em Florianópolis, SC, no período de 04 a 07 de agosto de 2013 - Universidade Federal de Santa ...
Essy, Gisele   +3 more
core  

Cannabinoid Actions on Neural Stem Cells: Implications for Pathophysiology

open access: yesMolecules, 2019
With the increase of life expectancy, neurodegenerative disorders are becoming not only a health but also a social burden worldwide. However, due to the multitude of pathophysiological disease states, current treatments fail to meet the desired outcomes.
Rui S. Rodrigues   +9 more
doaj   +1 more source

Multiscale Approximations to Understand the Complex Role of Microglia in Alzheimer's Disease

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 9, May 2026.
Microglia are dynamic, context‐dependent regulators of Alzheimer's disease, modulating amyloid, tau, and neurodegeneration across disease stages. Integrating multiscale and human‐focused approaches is essential to translate microglial biology into therapeutic strategies. ABSTRACT Microglia, the resident innate immune cells of the central nervous system,
Patricia Martínez‐Tazo   +9 more
wiley   +1 more source

Visual contrast sensitivity in tonic-clonic epileptic patients [PDF]

open access: yes, 2011
We measured the effects of epilepsy on visual contrast sensitivity to linear and vertical sine-wave gratings. Sixteen female adults, aged 21 to 50 years, comprised the sample in this study, including eight adults with generalized tonic-clonic seizure ...
ALENCAR, Caroline C. G.   +3 more
core   +1 more source

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