Results 41 to 50 of about 8,113 (115)

Workplace Protections and Burnout Among Brazilian Frontline Health Care Professionals During the COVID-19 Pandemic

open access: yesFrontiers in Psychology, 2022
Health care workers from low- and middle-income countries have been playing a critical role in overcoming the challenges related to the COVID-19 pandemic; yet little is known about the relationship between workplace protections and wellbeing of Brazilian
Karina Pereira-Lima   +6 more
doaj   +1 more source

Improving the clinical trial landscape for patients with atypical variants of Alzheimer's disease: a call to action

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Patients with atypical variants of Alzheimer's disease (AD) often present at a younger age with predominantly non‐amnestic impairments and a more aggressive disease course. Historically, individuals with atypical presentations have not been included in large‐scale clinical trials, which typically focus on late‐onset, sporadic amnestic ...
Nick Corriveau‐Lecavalier   +36 more
wiley   +1 more source

Effects of Cannabinoid Drugs on the Deficit of Prepulse Inhibition of Startle in an Animal Model of Schizophrenia: the SHR Strain

open access: yesFrontiers in Pharmacology, 2014
Clinical and neurobiological findings suggest that the cannabinoids and the endocannabinoid system may be implicated in the pathophysiology and treatment of schizophrenia.
Raquel eLevin   +14 more
doaj   +1 more source

Social vulnerability shapes deep clinical phenotypes and brain health in aging and dementia across Latin America

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Adverse social conditions across the life course influence brain aging and dementia, yet their compounded impact on clinical phenotypes remains underexplored, particularly in Latin America, where social inequality and dementia burden are high.
Temitope Farombi   +36 more
wiley   +1 more source

The include network: Advancing cross‐linguistic equity in brain health research

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Speech and language measures are increasingly recognized as sensitive, scalable, non‐invasive markers of diverse brain disorders. Yet, current research is overwhelmingly English‐centric, neglecting the world's vast linguistic diversity and undermining these markers’ global applicability.
Adolfo M. García   +13 more
wiley   +1 more source

White matter hyperintensities are associated with locus coeruleus atrophy and astrocytic β2‐adrenergic receptor expression

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION White matter hyperintensities (WMHs) are a robust marker of brain aging and dementia risk, typically attributed to vascular pathology. However, impaired astrocytic support may also contribute. The locus coeruleus (LC), which degenerates early in aging and Alzheimer's disease, provides widespread noradrenergic projections that ...
Victor Vidal   +16 more
wiley   +1 more source

Neurociências e psicanálise

open access: yesEstilos da Clínica, 2018
A partir de um entendimento integrativo entre psicanálise e neurociências, busca-se compreender a etiologia do autismo. Trata-se de uma revisão bibliográfica narrativa que abarcou dados da história e do conceito de autismo por meio de uma pesquisa ...
Marina da Rosa Vilani   +1 more
doaj   +1 more source

Vulnerability of the locus coeruleus–entorhinal cortex white matter tract in autosomal dominant Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Locus coeruleus (LC) structural integrity declines early in sporadic and autosomal dominant Alzheimer's disease (AD). We examined LC–entorhinal cortex (LC‐EC) tract integrity and its association with amyloid and tau pathology and memory in autosomal dominant AD (ADAD).
Elouise A. Koops   +11 more
wiley   +1 more source

Cannabinoid Actions on Neural Stem Cells: Implications for Pathophysiology

open access: yesMolecules, 2019
With the increase of life expectancy, neurodegenerative disorders are becoming not only a health but also a social burden worldwide. However, due to the multitude of pathophysiological disease states, current treatments fail to meet the desired outcomes.
Rui S. Rodrigues   +9 more
doaj   +1 more source

Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease

open access: yesNeuroprotection, Volume 4, Issue 2, Page 99-110, June 2026.
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García   +7 more
wiley   +1 more source

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