Results 11 to 20 of about 16,639 (150)

Association of the APOEε4 allele in Mexican‐mestizo older adults with subjective cognitive decline and mild cognitive impairment [PDF]

Alzheimers Dement
Abstract Background Subjective cognitive decline (SCD) is a state in which individuals complain of cognitive impairment; however, they perform normally on standard neuropsychological tests. SCD is considered a diagnostic entity of risk for mild cognitive impairment (MCI) and dementia.
Acosta‐Amaya Á, Sánchez‐Badajos S, Solano‐Mendoza D, Monroy‐Jaramillo N, Ortega‐Vázquez A, Infante‐Esquivel F, de Montellano D, Ruiz‐García R, Rodríguez‐Agudelo Y.   +8 more
europepmc   +2 more sources

Pharmacological management of tauopathies [PDF]

Alzheimers Dement
Abstract Tauopathies, a group of neurodegenerative disorders characterized by tau protein aggregation, encompass diseases such as progressive supranuclear palsy, and corticobasal degeneration. While the development of disease‐modifying therapies remains a primary research focus, current pharmacological interventions are predominantly directed towards ...
Rioja R, Morales‐Rivero A, Cordero I, Kovacs G, Tartaglia C, Couto B.   +5 more
europepmc   +2 more sources

Executive Functions in Latin American Older Adults: Exploring the Concept Shifting Test and Its Relationship with the APOE Gene in a Cross‐Sectional Sample from the LatAm‐FINGERS Study [PDF]

Alzheimers Dement
Abstract Background Latin America (LA) faces high vulnerability to dementia risk factors. Early detection of cognitive decline, particularly in executive functions (EF), is crucial. The Trail Making Test (TMT) has limitations, while the Concept Shifting Test (CST) offers potential advantages but lacks LA adaptation.
Cardoso D, Friedlaender C, Yassuda M, de Souza L, Crivelli L, Suemoto C, Martin M, Calandri I, Acosta‐Baena N, Surace E, Damian A, Martin M, Vigil‐Martinez A, Cançado G, Salinas‐Contreras R, Custodio B, Cusicanqui M, Delgado C, Leon‐Salas J, Duque L, Custodio N, Velazquez I, Charamelo A, Acosta D, Niño D, Sevlever G, Allegri R, Nitrini R, Sosa A, Gomes K, de Andrades A, Teixeira D, Figueiredo L, de Souza L, Jeunon V, Barbosa M, Vieira V, Lopes A, de Faria Rocha J, Prates M, Tossati J, Brucki S, Snyder H, Carrillo M, Kivipelto M, Caramelli P.   +45 more
europepmc   +2 more sources

Cardiovascular risk factors and the allostatic interoceptive network in dementia [PDF]

Alzheimers Dement
Abstract Background Cardiovascular risk factors, such diabetes, hypertension, blood pressure, obesity, and smoking, are linked with allostatic‐interoception – the continuous monitoring of internal bodily states in anticipation of environmental demands. These risk factors are associated with dementia risk.
Hazelton J, Migeot J, Gonzalez‐Gomez R, Altschuler F, Duran‐Aniotz C, Wen O, Rial D, Barttfeld P, Medel V, Campo C, Laguardia A, Hernandez H, Gonzalez‐Silva C, Castaner O, Hu K, Li P, Behrens M, Bruno M, Cardona J, Custodio N, Santamaria‐Garcia H, Garcia A, Godoy M, Alberto Ávila Funes J, Maito M, Matallana D, Miller B, Lopera F, de Oliveira M, Pina‐Escudero S, Possin K, de Paula E, Resende F, Reyes P, Slachevsky A, Sosa A, Takada L, Yokoyama J, Ibanez A.   +38 more
europepmc   +3 more sources

Clinical detection of PSP, not only an “atypical parkinsonism” [PDF]

Alzheimers Dement
Abstract Progressive Supranuclear Palsy (PSP) is a neurodegenerative condition that manifest motor, cognitive, and behavioral symptoms. Patients often suffer from early postural instability with falls, diplopia associated with oculomotor dysfunction, apathy, impulsivity, slowness of movement and of thought, as well as memory and language/communication ...
Couto B, Morales‐Rivero A, Flores I, Cordero I, Rioja R, Tartaglia C, Kovacs G.   +6 more
europepmc   +2 more sources

Baseline Results Investigate APOE‐Memory Connection in Latin‐American Population at Risk for Dementia ‐ LatAm‐FINGERS Initial Insights [PDF]

Alzheimers Dement
Abstract Background Latin America (LA) faces heightened vulnerability to modifiable dementia risk factors. Early identification of at‐risk individuals is crucial for implementing effective preventive strategies. The Free and Cued Selective Reminding Test with Immediate Recall (FCSRT‐IR) is promising in early detection of mnemonic impairment, with high ...
Friedlaender C, de Souza L, Barbosa M, Gomes K, Tosatti J, de Faria Rocha J, Cardoso D, Prates M, Lopes A, Vieira V, Jeunon V, de Souza L, Figueiredo L, de Andrades A, Teixeira D, Sosa A, Nitrini R, Allegri R, Sevlever G, Niño D, Acosta D, Crivelli L, Charamelo A, Jimenez‐Velazquez I, Custodio N, Duque L, Leon‐Salas J, Delgado C, Cusicanqui M, Custodio B, Salinas‐Contreras R, Cançado G, Vigil‐Martinez A, Martin M, Damian A, Surace E, Acosta‐Baena N, Calandri I, Yassuda M, Suemoto C, Martin M, Brucki S, Snyder H, Carrillo M, Kivipelto M, Caramelli P.   +45 more
europepmc   +2 more sources

Communication of prognosis to patient with PSP and family [PDF]

Alzheimers Dement
Abstract The prognosis of progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) involves a survival shorter than 10‐years since symptom onset with development of marked disability. Patients will often progress to require increased assisstance with daily living activities, and symptomatic therapies with partial effectiveness that lead to ...
Vargas‐González J, Flores I, Tartaglia C, Cordero I, Morales‐Rivero A, Rioja R, Couto B.   +6 more
europepmc   +2 more sources

Management of neurobehavioral changes in PSP [PDF]

Alzheimers Dement
Abstract Progressive supranuclear paralysis (PSP) is an atypical parkinsonian disorder associated with oculomotor features, postural instability along with cognitive problems and neuropsychiatric symptoms. Usually, the treatment focuses on motor symptoms, however addressing behavioral and cognitive symptoms could have a significant impact on ...
Morales‐Rivero A, Rioja R, Cordero I, Tartaglia C, Kovacs G, Couto B.   +5 more
europepmc   +2 more sources

Incidence of Creutzfeldt‐Jakob Disease in a Tertiary Care Referral Center in Mexico City [PDF]

Alzheimers Dement
Abstract Background Creutzfeldt‐Jakob disease (CJD) is a progressive, irreversible, and fatal disease associated with the misfolding of a protein in the central nervous system. Several surveillance programs emerged worldwide after the epidemic of the early 2000s. In Mexico, information about its epidemiology is scarce.
Hernandez I, Azuara E, Lucero H, Hernandez J, Rosales E, Garcia B, Rioja R.   +6 more
europepmc   +2 more sources

Conspiración de silencio y malestar emocional en pacientes diagnósticados de glioblastoma multiforme [PDF]

, 2012
Aim: For those patients suffering serious illnesses with a poor prognosis, there continues to be a significant percentage of well-meaning family members who, out of a desire to protect the patient, decide to hide the truth, even if the patient wishes to ...
Barcia Albacar, Juan Antonio, Barreto Martín, Pilar, Díaz Cordobés, José Luis, Gallego Sánchez, Jose María   +3 more
core   +2 more sources