Results 11 to 20 of about 17,207 (195)

Association of the APOEε4 allele in Mexican‐mestizo older adults with subjective cognitive decline and mild cognitive impairment [PDF]

Alzheimers Dement
Abstract Background Subjective cognitive decline (SCD) is a state in which individuals complain of cognitive impairment; however, they perform normally on standard neuropsychological tests. SCD is considered a diagnostic entity of risk for mild cognitive impairment (MCI) and dementia.
Acosta‐Amaya Á, Sánchez‐Badajos S, Solano‐Mendoza D, Monroy‐Jaramillo N, Ortega‐Vázquez A, Infante‐Esquivel F, de Montellano D, Ruiz‐García R, Rodríguez‐Agudelo Y.   +8 more
europepmc   +2 more sources

Pharmacological management of tauopathies [PDF]

Alzheimers Dement
Abstract Tauopathies, a group of neurodegenerative disorders characterized by tau protein aggregation, encompass diseases such as progressive supranuclear palsy, and corticobasal degeneration. While the development of disease‐modifying therapies remains a primary research focus, current pharmacological interventions are predominantly directed towards ...
Rioja R, Morales‐Rivero A, Cordero I, Kovacs G, Tartaglia C, Couto B.   +5 more
europepmc   +2 more sources

Executive Functions in Latin American Older Adults: Exploring the Concept Shifting Test and Its Relationship with the APOE Gene in a Cross‐Sectional Sample from the LatAm‐FINGERS Study [PDF]

Alzheimers Dement
Abstract Background Latin America (LA) faces high vulnerability to dementia risk factors. Early detection of cognitive decline, particularly in executive functions (EF), is crucial. The Trail Making Test (TMT) has limitations, while the Concept Shifting Test (CST) offers potential advantages but lacks LA adaptation.
Cardoso D, Friedlaender C, Yassuda M, de Souza L, Crivelli L, Suemoto C, Martin M, Calandri I, Acosta‐Baena N, Surace E, Damian A, Martin M, Vigil‐Martinez A, Cançado G, Salinas‐Contreras R, Custodio B, Cusicanqui M, Delgado C, Leon‐Salas J, Duque L, Custodio N, Velazquez I, Charamelo A, Acosta D, Niño D, Sevlever G, Allegri R, Nitrini R, Sosa A, Gomes K, de Andrades A, Teixeira D, Figueiredo L, de Souza L, Jeunon V, Barbosa M, Vieira V, Lopes A, de Faria Rocha J, Prates M, Tossati J, Brucki S, Snyder H, Carrillo M, Kivipelto M, Caramelli P.   +45 more
europepmc   +2 more sources

Physical Performance and its Association with Executive Function in Latin American Older Adults: Evidence from the LatAmFINGERS Multicenter Randomized Controlled Trial [PDF]

Alzheimers Dement
Abstract Background The accelerated aging process in low‐ and middle‐income countries (LMIC) has led to an increased prevalence of non‐communicable diseases, including dementia, a leading cause of disability in Latin America and the Caribbean (LAC). Executive and physical performance dysfunction accelerates functional decline in older adults.
Gutiérrez M, Marroig A, Concha N, Delgado C, Charamelo A, Burgos P, Slachevsky A, Dansilio S, Lema J, Martinez M, Márquez C, Castro N, Moreno M, Bravo J, Lara O, More J, Acosta‐Baena N, Crivelli L, Calandri I, Sevlever G, Aguillon D, Allegri R, Caramelli P, Nitrini R, Sosa‐Ortiz A, Salinas‐Contreras R, Suemoto C, Yassuda M.   +27 more
europepmc   +3 more sources

Clinical detection of PSP, not only an “atypical parkinsonism” [PDF]

Alzheimers Dement
Abstract Progressive Supranuclear Palsy (PSP) is a neurodegenerative condition that manifest motor, cognitive, and behavioral symptoms. Patients often suffer from early postural instability with falls, diplopia associated with oculomotor dysfunction, apathy, impulsivity, slowness of movement and of thought, as well as memory and language/communication ...
Couto B, Morales‐Rivero A, Flores I, Cordero I, Rioja R, Tartaglia C, Kovacs G.   +6 more
europepmc   +2 more sources

Baseline Results Investigate APOE‐Memory Connection in Latin‐American Population at Risk for Dementia ‐ LatAm‐FINGERS Initial Insights [PDF]

Alzheimers Dement
Abstract Background Latin America (LA) faces heightened vulnerability to modifiable dementia risk factors. Early identification of at‐risk individuals is crucial for implementing effective preventive strategies. The Free and Cued Selective Reminding Test with Immediate Recall (FCSRT‐IR) is promising in early detection of mnemonic impairment, with high ...
Friedlaender C, de Souza L, Barbosa M, Gomes K, Tosatti J, de Faria Rocha J, Cardoso D, Prates M, Lopes A, Vieira V, Jeunon V, de Souza L, Figueiredo L, de Andrades A, Teixeira D, Sosa A, Nitrini R, Allegri R, Sevlever G, Niño D, Acosta D, Crivelli L, Charamelo A, Jimenez‐Velazquez I, Custodio N, Duque L, Leon‐Salas J, Delgado C, Cusicanqui M, Custodio B, Salinas‐Contreras R, Cançado G, Vigil‐Martinez A, Martin M, Damian A, Surace E, Acosta‐Baena N, Calandri I, Yassuda M, Suemoto C, Martin M, Brucki S, Snyder H, Carrillo M, Kivipelto M, Caramelli P.   +45 more
europepmc   +2 more sources

Communication of prognosis to patient with PSP and family [PDF]

Alzheimers Dement
Abstract The prognosis of progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) involves a survival shorter than 10‐years since symptom onset with development of marked disability. Patients will often progress to require increased assisstance with daily living activities, and symptomatic therapies with partial effectiveness that lead to ...
Vargas‐González J, Flores I, Tartaglia C, Cordero I, Morales‐Rivero A, Rioja R, Couto B.   +6 more
europepmc   +2 more sources

Exploring the Reliability of Self‐Reported Physical Activity in Aging Populations: A Chilean Cohort Approach [PDF]

Alzheimers Dement
Abstract Background Physical activity (PA) is a well‐established factor that can help mitigate cognitive decline in aging populations. However, the relationship between PA, sex differences, and cognitive performance remains inadequately explored in underrepresented populations, such as in Latin America.
Rogers N.
europepmc   +2 more sources

Management of neurobehavioral changes in PSP [PDF]

Alzheimers Dement
Abstract Progressive supranuclear paralysis (PSP) is an atypical parkinsonian disorder associated with oculomotor features, postural instability along with cognitive problems and neuropsychiatric symptoms. Usually, the treatment focuses on motor symptoms, however addressing behavioral and cognitive symptoms could have a significant impact on ...
Morales‐Rivero A, Rioja R, Cordero I, Tartaglia C, Kovacs G, Couto B.   +5 more
europepmc   +2 more sources

In vivo measurement of human brain elasticity using a light aspiration device [PDF]

, 2009
The brain deformation that occurs during neurosurgery is a serious issue impacting the patient "safety" as well as the invasiveness of the brain surgery. Model-driven compensation is a realistic and efficient solution to solve this problem.
Boudou, Thomas, Chassat, Fabrice, Payan, Yohan, Promayon, Emmanuel, Schiavone, Patrick, Valdivia, F.   +5 more
core   +3 more sources