Results 151 to 160 of about 3,341,463 (362)

sEEG‐guided responsive neurostimulation to treat neocortical epilepsy: A multicenter retrospective study of the efficacy and safety of depth electrode‐mediated neuromodulation

open access: yesEpilepsia Open, EarlyView.
Abstract Objectives Pivotal trials have established the effectiveness of the Responsive Neurostimulation System (RNS® System) in treating focal epilepsy. In clinical trials, depth leads were primarily used to treat mesial temporal seizure onsets while cortical strip leads were used to treat neocortical seizure onsets.
Sina Sadeghzadeh   +30 more
wiley   +1 more source

Blood metabolites, neurocognition and psychiatric disorders: a Mendelian randomization analysis to investigate causal pathways

open access: yesTranslational Psychiatry
Background Neurocognitive dysfunction is observationally associated with the risk of psychiatric disorders. Blood metabolites, which are readily accessible, may become highly promising biomarkers for brain disorders.
Jing Guo   +12 more
doaj   +1 more source

Natural language processing‐based emotion and usage analysis of an AI‐powered chatbot for epilepsy support

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Artificial intelligence (AI)‐powered chatbots are increasingly used for patient education and mental health support, yet their effectiveness in epilepsy care remains underexplored. This study examines text‐based interactions between users and EpiloBot, an epilepsy‐focused chatbot, to understand conversational patterns and emotional ...
Keiichi Watanuki   +10 more
wiley   +1 more source

Areas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, EpiCARE

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To define and articulate research priorities in epilepsy identified by the European Reference Network for Rare and Complex Epilepsies (ERN EpiCARE), addressing key unmet needs across the spectrum of rare and complex epilepsies. Methods This position paper was developed through a structured collaborative process involving patient ...
Sébile Tchaicha   +27 more
wiley   +1 more source

Recent Insights into Hippocampal Dysfunction and Neuroplasticity in Sleep Disorders: An Update from Preclinical Studies

open access: yesJournal of Integrative Neuroscience
Sleep disorders are prevalent neurological conditions linked to neurocognitive impairments. Understanding the neuroplasticity changes in the hippocampus, which plays a central role in regulating neurocognitive function, is crucial in the context of sleep
Poornima D. E. Weerasinghe-Mudiyanselage   +1 more
doaj   +1 more source

Naturalistic Associations Between Childhood Maltreatment, Compulsivity, and Eating Disorder Symptoms Over a 12‐Months Period Among Individuals With Anorexia Nervosa

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Introduction Childhood maltreatment is associated with more severe eating disorder (ED) symptoms and compulsivity, and compulsivity is implicated in anorexia nervosa (AN). However, the role of childhood maltreatment and compulsivity in shaping the clinical course of AN remains unclear.
Elizabeth N. Dougherty   +6 more
wiley   +1 more source

TREM1—Microglia crosstalk: Neurocognitive disorders

open access: yesBrain Research Bulletin
Neurocognitive Disorders (NCDs) primarily affect cognitive functions, including learning, memory, perception, and problem-solving. They predominantly arise as pathological sequelae of central nervous system (CNS) disorders.
Huashan Li   +3 more
doaj   +1 more source

Identifying Distinct Latent Profiles of Executive Functioning Among Adolescents and Adults With Anorexia Nervosa and Adolescent Healthy Controls

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Research suggests executive functioning (EF) inefficiencies contribute to anorexia nervosa (AN) onset and maintenance. Identifying EF subtypes in adolescents and adults with AN compared to healthy controls (HC) may provide insights into differences in illness severity, risk for prolonged illness, and highlight who could respond best ...
Jiana Schnabel   +7 more
wiley   +1 more source

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