Results 21 to 30 of about 10,696 (183)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
DEVELOPMENT OF NEUROCRITICAL CARE
Annals of the Russian academy of medical sciences, 2012 In this review we provide the definition, goals and objectives of neurocritical care, evaluation of brief history of its development. Mechanical ventilation, intracranial hypertension, neuromonitoring as underlying basics of neurocritical care approaches are discussed.
M A, Piradov, V V, Moroz
openaire +3 more sources
Clinical NeuroimagingIntroduction Neurosonology has emerged as an important bedside tool in neurocritical care, offering real‐time insights into cerebral hemodynamics and intracranial physiology.
Yasaman Pirahanchi +14 more
doaj +1 more source
Frontiers in MedicineBackgroundStroke-associated pneumonia (SAP) is a frequent and devastating complication after acute stroke. Although early dysphagia screening is strongly recommended by guidelines, its implementation is often delayed in the Neurological Intensive Care ...
Bo Gao +7 more
doaj +1 more source
Annals of the Child Neurology Society, EarlyView.ABSTRACT Objective Seizures represent a significant source of morbidity for children with brain tumors. The objective of our study was to establish consensus guidelines for managing children with tumor‐related epilepsy. Methods The study team assembled a panel of 18 child neurologists specializing in neurological complications of brain tumors including
Stephanie N. Brosius +4 more
wiley +1 more source
Pathobiology of traumatic spinal cord injury: an overview
Egyptian Journal of NeurosurgeryTraumatic spinal cord injury (SCI) or traumatic myelopathy is a devastating neurological condition and a heavy burden on the health system. There are inflammatory and structural biomarkers with well-defined profiles, and useful for determining the ...
William A. Florez-Perdomo +8 more
doaj +1 more source
Improved Outcomes following the Establishment of a Neurocritical Care Unit in Saudi Arabia
Critical Care Research and Practice, 2018 Background. Dedicated neurocritical care units have dramatically improved the management and outcome following brain injury worldwide. Aim. This is the first study in the Middle East to evaluate the clinical impact of a neurocritical care unit (NCCU ...
Ibrahim Soliman +9 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is commonly used for secondary prevention following acute ischemic stroke (AIS) and neurointerventional procedures. However, the efficacy of clopidogrel is reduced in carriers of CYP2C19 no‐function alleles.
Rachael M. Stone +11 more
wiley +1 more source
Epileptic Disorders, EarlyView.Abstract Objective To assess informed acceptance and perceptions of the 2025 update of the International League Against Epilepsy (ILAE) seizure classification—after participants had received a focused educational introduction to the updated classification. Methods We analyzed anonymized live poll responses from two educational webinars dedicated to the
Sándor Beniczky +6 more
wiley +1 more source
Localizing value of cutaneous ictal phenomena: A systematic review
Epileptic Disorders, EarlyView.Abstract Objective Clinical observation of autonomic signs during seizures can aid in localizing the epileptogenic zone (EZ). We performed a systematic review and meta‐analysis to evaluate the localizing value of ictal cutaneous phenomena—piloerection, sweating, pallor, and flushing—in focal epilepsy and their relevance to presurgical evaluation ...
R. Rocamora +7 more
wiley +1 more source