Results 21 to 30 of about 1,446 (155)
Author Response: The Neurodata Without Borders Ecosystem for Neurophysiological Data Science
Ryan Ly +2 more
exaly +2 more sources
IntroductionThe study of the brain continues to generate substantial volumes of data, commonly referred to as “big brain data,” which serves various purposes such as the treatment of brain-related diseases, the development of neurotechnological devices ...
Paschal Ochang +3 more
doaj +1 more source
Unusual Mathematical Approaches Untangle Nervous Dynamics
The massive amount of available neurodata suggests the existence of a mathematical backbone underlying neuronal oscillatory activities. For example, geometric constraints are powerful enough to define cellular distribution and drive the embryonal ...
Arturo Tozzi, Lucio Mariniello
doaj +1 more source
Development of the Neurodata Without Borders: Neurophysiology File Format
Teeters Jeffrey +6 more
exaly +2 more sources
Italian, European, and international neuroinformatics efforts: An overview
The advent of the Big Data phenomenon, combined with technological improvements, has enabled researchers and clinicians to collect data more cheaply and quickly than a decade ago. Thanks to numerous efforts at the national and international levels, several neuroinformatics platforms have been developed to exploit this ‘data deluge’ and provide tools ...
Alberto Redolfi +9 more
wiley +1 more source
The Neurodata Without Borders ecosystem for neurophysiological data science [PDF]
Abstract The neurophysiology of cells and tissues are monitored electrophysiologically and optically in diverse experiments and species, ranging from flies to humans. Understanding the brain requires integration of data across this diversity, and thus these data must be findable, accessible, interoperable, and reusable (FAIR).
Oliver Rübel +9 more
openaire +1 more source
Abstract Time–frequency representations of electroencephalographic signals lend themselves to a granular analysis of cognitive and psychological processes. Characterizing developmental trajectories of time–frequency measures can thus inform us about the development of the processes involved as well as correlated traits and behaviors.
Stephen M. Malone +2 more
wiley +1 more source
Hallmarks of neurodegenerative disease: A systems pharmacology perspective
Abstract Age‐related central neurodegenerative diseases, such as Alzheimer's and Parkinson's disease, are a rising public health concern and have been plagued by repeated drug development failures. The complex nature and poor mechanistic understanding of the etiology of neurodegenerative diseases has hindered the discovery and development of effective ...
Peter Bloomingdale +14 more
wiley +1 more source
Imagined paralysis reduces motor cortex excitability
Abstract Mental imagery is a powerful capability that engages similar neurophysiological processes that underlie real sensory and motor experiences. Previous studies show that motor cortical excitability can increase during mental imagery of actions. In this study, we focused on possible inhibitory effects of mental imagery on motor functions.
Matthias Hartmann +4 more
wiley +1 more source
Astrocyte reactivity in a mouse model of SCN8A epileptic encephalopathy
Abstract Objective SCN8A epileptic encephalopathy is caused predominantly by de novo gain‐of‐function mutations in the voltage‐gated sodium channel Nav1.6. The disorder is characterized by early onset of seizures and developmental delay. Most patients with SCN8A epileptic encephalopathy are refractory to current anti‐seizure medications.
Jeremy A. Thompson +6 more
wiley +1 more source

