Results 41 to 50 of about 1,109 (123)
Sleep Deprivation Influences Circadian Gene Expression in the Lateral Habenula
Behavioural Neurology, Volume 2016, Issue 1, 2016., 2016 Sleep is governed by homeostasis and the circadian clock. Clock genes play an important role in the generation and maintenance of circadian rhythms but are also involved in regulating sleep homeostasis. The lateral habenular nucleus (LHb) has been implicated in sleep‐wake regulation, since LHb gene expression demonstrates circadian oscillation ...
Beilin Zhang +5 more
wiley +1 more source
BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease
Alzheimer's &Dementia, Volume 20, Issue 4, Page 2922-2942, April 2024.Abstract INTRODUCTION The BIN1 coding variant rs138047593 (K358R) is linked to Late‐Onset Alzheimer's Disease (LOAD) via targeted exome sequencing. METHODS To elucidate the functional consequences of this rare coding variant on brain amyloidosis and neuroinflammation, we generated BIN1K358R knock‐in mice using CRISPR/Cas9 technology.
Laura Fernandez Garcia‐Agudo +26 more
wiley +1 more source
Oltre il forum internum: libertà cognitiva e stati mentali pre-espressivi
Aequitas MagazineThis article addresses whether and to what extent pre-expressive mental states – cognitive, emotional and deliberative processes that unfold prior to any externalisation of thought – can be adequately protected within existing constitutional frameworks ...
Luigi Zito
doaj +1 more source
C5aR1 signaling promotes region‐ and age‐dependent synaptic pruning in models of Alzheimer's disease
Alzheimer's &Dementia, Volume 20, Issue 3, Page 2173-2190, March 2024.Abstract INTRODUCTION Synaptic loss is a hallmark of Alzheimer's disease (AD) that correlates with cognitive decline in AD patients. Complement‐mediated synaptic pruning has been associated with this excessive loss of synapses in AD. Here, we investigated the effect of C5aR1 inhibition on microglial and astroglial synaptic pruning in two mouse models ...
Angela Gomez‐Arboledas +7 more
wiley +1 more source
Interconnecting Neuromanagement and Time Series Modelling: Analysis of Research Trends and Methodologies [PDF]
Marketing i Menedžment InnovacijNeuromanagement is an interdisciplinary field that integrates neuroscience, management, and psychology, demonstrating significant growth potential in developing human capital and enhancing organizational effectiveness.
doaj +1 more source
Age of Human Rights JournalThe present paper is concerned with the ongoing debate on neurorights from the standpoint of legal philosophy. The fundamental question is whether these rights should be understood as a reinterpretation of existing fundamental rights or as a distinct ...
Antonio Tirso Ester Sánchez
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Visualizing and sonifying neurodata (ViSoND) for enhanced observation
Abstract Neuroscience needs observation. Observation lets us evaluate data quality, judge whether models are biologically realistic, and generate new hypotheses. However, high-dimensional behavioral and neural data are too complex to be easily displayed and eye-tested.
Leah Blankenship +7 more
openaire +1 more source
International Journal of Advanced Business StudiesThe emerging neurotechnology industry, led by firms like Neuralink, is rapidly transitioning from purely medical applications to the broader consumer market of human enhancement.
Edward Musole
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Semantic Federation of Distributed Neurodata
, 2012 Neurodata repositories federation is increasingly needed to implement multi-centric studies. Data federation is difficult due to the heterogeneous nature of distributed data repositories and the technical difficulties faced in addressing simultaneously multiple data sources.
Gaignard, Alban +3 more
openaire +1 more source
Scientific DataThe link between comprehensive behavioral measurements during a behavioral task and brain-wide neuronal activity is an essential strategy to better understand the brain dynamics underlying the emergence of behavior changes.
Masashi Kondo +7 more
doaj +1 more source