Results 51 to 60 of about 1,446 (155)
, 2015 Computational Statistics for Whole Brain CLARITY Imaging using the Open Connectome Project ...
NeuroData (96497)
core +1 more source
The leptin sensitizer celastrol reduces age‐associated obesity and modulates behavioral rhythms
Aging Cell, Volume 18, Issue 3, June 2019., 2019 Abstract The prevalence of obesity increases with age in humans and in rodents. Age‐related obesity is characterized by leptin resistance and associated with heightened risk of metabolic disorders. However, the effect of leptin resistance per se has been difficult to disentangle from other effects of aging. Here we demonstrate that celastrol, a natural
Karthikeyani Chellappa +3 more
wiley +1 more source
, 2017 <p>Compatible with <a href="https://github.com/neurodata/ndio">ndio</a> <strong>Note: From this release all cutout services have moved to /sd/ from /ca/ and to /nd/ from /ocp/.</strong></p> Features <ul> <li ...
pmanava1 +9 more
core +1 more source
Credibility-Adjusted Data-Conscious Clustering Method for Robust EEG Signal Analysis
IEEE AccessClustering neurodata, including electroencephalography (EEG) signals, is crucial for brain-computer interface (BCI) and neurological analysis. However, traditional methods struggle with noise, overlapping distributions, and high-dimensional data.
Fatemeh Divan +3 more
doaj +1 more source
Sleep Deprivation Influences Circadian Gene Expression in the Lateral Habenula
Behavioural Neurology, Volume 2016, Issue 1, 2016., 2016 Sleep is governed by homeostasis and the circadian clock. Clock genes play an important role in the generation and maintenance of circadian rhythms but are also involved in regulating sleep homeostasis. The lateral habenular nucleus (LHb) has been implicated in sleep‐wake regulation, since LHb gene expression demonstrates circadian oscillation ...
Beilin Zhang +5 more
wiley +1 more source
Web Visualization of Massive Neuroscience Datasets using the Open Connectome Project & NeuroData
, 2015 Web Visualization of Massive Neuroscience Datasets using the Open Connectome Project ...
Alex Baden (818385), NeuroData (96497)
core +1 more source
, 2020 This repository is meant as an archive to the neuroparc repository found here: https://github.com/neurodata/neuroparc/ The purpose of this repository is to create a single location where a wide variety of brain atlases/parcellations can be found with ...
NeuroData
core +1 more source
BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease
Alzheimer's &Dementia, Volume 20, Issue 4, Page 2922-2942, April 2024.Abstract INTRODUCTION The BIN1 coding variant rs138047593 (K358R) is linked to Late‐Onset Alzheimer's Disease (LOAD) via targeted exome sequencing. METHODS To elucidate the functional consequences of this rare coding variant on brain amyloidosis and neuroinflammation, we generated BIN1K358R knock‐in mice using CRISPR/Cas9 technology.
Laura Fernandez Garcia‐Agudo +26 more
wiley +1 more source
C5aR1 signaling promotes region‐ and age‐dependent synaptic pruning in models of Alzheimer's disease
Alzheimer's &Dementia, Volume 20, Issue 3, Page 2173-2190, March 2024.Abstract INTRODUCTION Synaptic loss is a hallmark of Alzheimer's disease (AD) that correlates with cognitive decline in AD patients. Complement‐mediated synaptic pruning has been associated with this excessive loss of synapses in AD. Here, we investigated the effect of C5aR1 inhibition on microglial and astroglial synaptic pruning in two mouse models ...
Angela Gomez‐Arboledas +7 more
wiley +1 more source
Oltre il forum internum: libertà cognitiva e stati mentali pre-espressivi
Aequitas MagazineThis article addresses whether and to what extent pre-expressive mental states – cognitive, emotional and deliberative processes that unfold prior to any externalisation of thought – can be adequately protected within existing constitutional frameworks ...
Luigi Zito
doaj +1 more source