Differential Mechanisms of Neuroprotection by 17 β-Estradiol in Apoptotic versus Necrotic Neurodegeneration [PDF]
Christoph Harms+10 more
openalex +1 more source
m6A Methylation‐Induced Autophagy Impairment by TFEB Regulation in SOD1‐G93A ALS Cell Model
ABSTRACT We investigate the role of m6A RNA methylation in regulating transcription factor EB (TFEB) and its contribution to mitochondrial autophagy (mitophagy) dysfunction in amyotrophic lateral sclerosis (ALS). ALS cell models were used to analyse mitophagy markers and TFEB expression under METTL3 and TFEB modulation, using RT‐qPCR, Western blot ...
Di An+7 more
wiley +1 more source
Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer's Disease Models. [PDF]
Abdul-Nasir S+9 more
europepmc +1 more source
Green tea polyphenol (–)‐epigallocatechin‐3‐gallate prevents N‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐induced dopaminergic neurodegeneration [PDF]
Yona Levites+4 more
openalex +1 more source
Diglycerides of Natural Phenols and Organic Acids for Enhanced Biological Activities
Diglycerides of natural organic acids and phenols were synthesized regio‐selectively. Diglycerides are structurally similar to cell membranes and are expected to exhibit cell affinity and permeability. The flexible glycerol linkers allow the diglycerides to exhibit not only the physiological activities of each constituent organic acid but also the ...
Jisu Hong+10 more
wiley +1 more source
Correction to: Optical coherence tomography with voxel-based morphometry: a new tool to unveil focal retinal neurodegeneration in multiple sclerosis. [PDF]
europepmc +1 more source
Adverse childhood experiences influence markers of neurodegeneration risk in older adults. [PDF]
Rose DK+8 more
europepmc +1 more source
Toward an Understanding of Polyglutamine Neurodegeneration
Henry L. Paulson
openalex +2 more sources
Olfactory Impairment and Incident Cognitive Decline: A Systematic Review and Meta‐Analysis
ABSTRACT Background Olfactory impairment (OI) is associated with poor ageing outcomes. While cross‐sectional studies found a high prevalence of OI among patients with neurodegenerative diseases, the temporal relationship remains unclear. This meta‐analysis aims to synthesise the longitudinal association of OI with cognitive decline (CD). Methods PubMed,
Brian Sheng Yep Yeo+17 more
wiley +1 more source
NEDD4L induces mitochondrial dysfunction and neurodegeneration by promoting LIPT2 degradation in Huntington's disease. [PDF]
Fan P+8 more
europepmc +1 more source