Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease
Cell Death and Differentiation, 2020 Jaydeep Sidhaye, Jurgen Knoblich
semanticscholar +1 more source
Alternative Developmental Toxicity Screening Methods Using Chick Embryo‐Based Models
Journal of Applied Toxicology, EarlyView.ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Jeong Hwan Kim +4 more
wiley +1 more source
Antenatal depressive symptoms impair offspring neurodevelopment by inducing maternal gut microbiota dysbiosis during pregnancy. [PDF]
Gut MicrobesZhou F +13 more
europepmc +1 more source
Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals
Journal of Applied Toxicology, EarlyView.ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice +8 more
wiley +1 more source
No significant impact of levothyroxine treatment of maternal subclinical hypothyroidism on brain morphology in adolescence: insight from long-term follow up of Controlled Antenatal Thyroid Screening (CATS) study. [PDF]
Ann Transl MedLee SY.
europepmc +1 more source
JCPP Advances, EarlyView.Abstract Background The cumulative effect of early medical events has been shown to be associated with autism. It is unclear whether this effect is specific to autism or if it is associated to other neurodevelopmental conditions (NDCs) as well. Methods We established a registry‐linked population‐based twin cohort of 10,254 pairs within the child and ...
Torkel Carlsson +4 more
wiley +1 more source
Toward a Rigorous Framework for Studying the Gut-Brain Axis, Environmental Exposures, and Attention-Deficit/Hyperactivity Disorder. [PDF]
Biol Psychiatry Glob Open SciGur TL.
europepmc +1 more source
Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder
JCPP Advances, EarlyView.Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista +5 more
wiley +1 more source
Special Issue: Genetic Basis of Autism Spectrum Disorder. [PDF]
Int J Mol SciBolognesi E, Guerini FR.
europepmc +1 more source
JCPP Advances, EarlyView.This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf +5 more
wiley +1 more source