Results 191 to 200 of about 114,486 (309)

AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment

Nature, 2020
Catherine R. Lammert, Elizabeth L. Frost, C. Bellinger, Ashley C. Bolte, Celia A. McKee, Mariah E. Hurt, Matt J. Paysour, Hannah E Ennerfelt, J. Lukens   +8 more
semanticscholar   +1 more source

Epileptic encephalopathy with spike‐and‐wave activation in sleep associated with Tatton–Brown–Rahman syndrome responsive to highly purified cannabidiol

Epileptic Disorders, EarlyView.
Anita N. Datta
wiley   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

Unveiling sleep disturbances in KCNB1‐related disorders: Insights from a cohort of 78 individuals

Epilepsia Open, EarlyView.
Abstract Objectives Sleep disturbances are frequent comorbidities in epilepsies and developmental encephalopathies. This study aimed to characterize sleep abnormalities in individuals with KCNB1‐related disorders, focusing on their prevalence, clinical manifestations, and impact on daily functioning.
Giovanna Scorrano, Delphine Breuillard, Anais Thimon, Nicole Chemaly, Rima Nabbout   +4 more
wiley   +1 more source

Very Preterm Infant Retinal Microanatomy at 36 Weeks' Postmenstrual Age and 2-Year Neurodevelopment. [PDF]

JAMA Ophthalmol
Gustafson KE, Sarin N, He J, Ying GS, Tai V, Winter KP, Cotten CM, Toth CA, BabySTEPS Group.   +8 more
europepmc   +1 more source

Probiotics, prematurity and neurodevelopment: Follow-up of a randomised trial

, 2017
Probiotics, prematurity and neurodevelopment: Follow-up of a randomised ...
J Bowen (12148239), KL Sia (14452887), E Carse (13560208), L Hickey (11189874), CJ Morley (15870758), J Sinn (13560220), J Levison (13560223), PJ Anderson (12502594), JM Tobin (9999965), MJ Buksh (15870782), K Tan (7719896), SN Tabrizi (9898643), JA Stack (15870767), NC Austin (15870773), MLK Tang (14455860), IMR Wright (15870761), A Veldman (13560205), JM Alsweiler (15870779), SM Garland (9898652), GF Opie (14539637), DA Osborn (15870764), S Donath (10000292), Lisa Gold (13071603), A Lewis (5218952), JLY Cheong (14003757), AG DePaoli (15870770), J Travadi (13560211), BA Darlow (15870776), SE Jacobs (14454207), M Pirotta (13312713)   +29 more
core  

Beyond seizures: A multidimensional approach to non‐seizure issues in Lennox–Gastaut syndrome. Insights from Italian experts

Epilepsia Open, EarlyView.
Abstract Non‐seizure issues (NSIs), including cognition, behavior/psychiatric symptoms, adaptive and social functioning, sleep, autonomic, and motor impairments, often shape day‐to‐day outcomes in Lennox–Gastaut syndrome (LGS) more than seizures, yet clinicians lack LGS‐specific, feasible assessment pathways.
Giancarlo Di Gennaro, Domenica Immacolata Battaglia, Paolo Bonanni, Gian Marco Duma, Antonietta Coppola, Edoardo Ferlazzo, Dario Pruna, Carlo Di Bonaventura   +7 more
wiley   +1 more source

Parental microbiome programming of early-life neurodevelopment: multi-niche contributions through the microbiome-gut-brain axis. [PDF]

Gut Microbes
Skrabulyte-Barbulescu J, Yassin LK, Almazrouei S, Alkuwaiti SH, Almarzooqi S, Alnuaimi F, Alketbi S, Nakhal MM, Rutkowska-Gauvry P, Matar SA, Hamad MIK.   +10 more
europepmc   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Dynamics of early gut microbiota maturation in extremely preterm infants and neurodevelopment at 2 years of age in a probiotic intervention trial. [PDF]

iScience
Abrahamsson T, Wejryd E, Pujolassos M, Calle ML, Sverremark-Ekström E, Jenmalm MC, Martí M.   +6 more
europepmc   +1 more source